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Editorials
The pathophysiology of acute heart failure—It is a lot about fluid accumulation, 22 November 2007 Marco Metra, Livio Dei Cas, Michael R. Bristow pages 1-5 Full Text | Full-Text PDF (106 KB)
Establishing the effectiveness of coronary intervention for acute myocardial infarction William S. Weintraub, Deborah Ehrenthal pages 6-8 Full Text | Full-Text PDF (70 KB)
Curriculum in Cardiology
The pathophysiology of acute heart failure—Is it all about fluid accumulation? Gad Cotter, G. Michael Felker, Kirkwood F. Adams, Olga Milo-Cotter, Christopher M. O'Connor pages 9-18 Abstract | Full Text | Full-Text PDF (532 KB)
Trial Design
Rationale and design of the Trial of Routine ANgioplasty and Stenting After Fibrinolysis to Enhance Reperfusion in Acute Myocardial Infarction (TRANSFER-AMI), 26 October 2007 Warren J. Cantor, David Fitchett, Bjug Borgundvaag, Michael Heffernan, Eric A. Cohen, Laurie J. Morrison, Anatoly Langer, Shamir Mehta, Charles Lazzam, Brian Schwartz, Vladimir Dzavik, Shaun G. Goodman pages 19-25 Abstract | Full Text | Full-Text PDF (254 KB)
Rationale, design, and baseline characteristics for a large international trial of cardiovascular disease prevention in people with dysglycemia: The ORIGIN Trial (Outcome Reduction with an Initial Glargine Intervention), 23 November 2007 The ORIGIN Trial Investigators pages 26.e1-26.e13 Abstract | Full Text | Full-Text PDF (188 KB)
Monitoring the ACTIVE-W trial: Some issues in monitoring a noninferiority trial, 23 November 2007 John A. Cairns, Janet Wittes, D. George Wyse, Janet Pogue, Michael Gent, Jack Hirsh, John Marler, Edward L.C. Pritchett pages 33-41 Abstract | Full Text | Full-Text PDF (250 KB)
Clinical Investigations
Acute Ischemic Heart Disease
Comparing invasive and noninvasive management strategies for acute myocardial infarction using administrative databases Louise Pilote, Christine A. Beck, Mark J. Eisenberg, Karin Humphries, Lawrence Joseph, John R. Penrod, Jack V. Tu pages 42-48 Abstract | Full Text | Full-Text PDF (130 KB)
Myeloid-related protein 8/14 and the risk of cardiovascular death or myocardial infarction after an acute coronary syndrome in the Pravastatin or Atorvastatin Evaluation and Infection Theraphy: Thrombolysis in Myocardial Infarction (PROVE IT-TIMI 22) trial, 12 October 2007 David A. Morrow, Yunmei Wang, Kevin Croce, Masashi Sakuma, Marc S. Sabatine, Huiyun Gao, Aruna D. Pradhan, Aileen M. Healy, Jacki Buros, Carolyn H. McCabe, Peter Libby, Christopher P. Cannon, Eugene Braunwald, Daniel I. Simon pages 49-55 Abstract | Full Text | Full-Text PDF (300 KB) | Add-Ons
Inflammatory responses after intracoronary injection of autologous mononuclear bone marrow cells in patients with acute myocardial infarction Svein Solheim, Ingebjørg Seljeflot, Ketil Lunde, Pål Aukrust, Arne Yndestad, Haakon Kiil Grøgaard, Svend Aakhus, Kolbjørn Forfang, Harald Arnesen pages 55.e1-55.e9 Abstract | Full Text | Full-Text PDF (264 KB)
Biomarker analysis by fluorokine multianalyte profiling distinguishes patients requiring intervention from patients with long-term quiescent coronary artery disease: A potential approach to identify atherosclerotic disease progression, 08 October 2007 Paul A. Gurbel, Rolf P. Kreutz, Kevin P. Bliden, Joseph DiChiara, Udaya S. Tantry pages 56-61 Abstract | Full Text | Full-Text PDF (127 KB)
Coronary Artery Disease
Kidney dysfunction and fatal cardiovascular disease—an association independent of atherosclerotic events: Results from the Health, Aging, and Body Composition (Health ABC) study, 08 October 2007 Rajat Deo, Christina L. Wassel Fyr, Linda F. Fried, Anne B. Newman, Tamara B. Harris, Sara Angleman, Christie Green, Stephen B. Kritchevsky, Glenn M. Chertow, Steven R. Cummings, Michael G. Shlipak, for the Health ABC study pages 62-68 Abstract | Full Text | Full-Text PDF (165 KB)
Congestive Heart Failure
Recovery of normal ventricular function in patients with dilated cardiomyopathy: Predictors of an increasingly prevalent clinical event, 28 September 2007 Philip F. Binkley, Amanda Lesinski, Jeanette Pohorence Ferguson, Patricia S. Hatton, Laura Yamokoski, Sheetal Hardikar, Glen E. Cooke, Carl V. Leier pages 69-74 Abstract | Full Text | Full-Text PDF (122 KB)
Pentraxin 3, a new marker for vascular inflammation, predicts adverse clinical outcomes in patients with heart failure, 28 September 2007 Satoshi Suzuki, Yasuchika Takeishi, Takeshi Niizeki, Yo Koyama, Tatsuro Kitahara, Toshiki Sasaki, Mina Sagara, Isao Kubota pages 75-81 Abstract | Full Text | Full-Text PDF (426 KB)
Cystatin C and risk of heart failure in the Physicians' Health Study (PHS), 08 October 2007 Luc Djoussé, Tobias Kurth, J. Michael Gaziano pages 82-86 Abstract | Full Text | Full-Text PDF (120 KB)
Amiodarone use after acute myocardial infarction complicated by heart failure and/or left ventricular dysfunction may be associated with excess mortality, 26 October 2007 Kevin L. Thomas, Sana M. Al-Khatib, Yuliya Lokhnygina, Scott D. Solomon, Lars Kober, John J.V. McMurray, Robert M. Califf, Eric J. Velazquez pages 87-93 Abstract | Full Text | Full-Text PDF (223 KB)
Diabetes and Metabolism
Effects of clopidogrel and aspirin in combination versus aspirin alone on platelet activation and major receptor expression in diabetic patients: The PLavix Use for Treatment Of Diabetes (PLUTO-Diabetes) Trial, 19 November 2007 Victor L. Serebruany, Alex I. Malinin, Alex Pokov, Gregory Barsness, Dan F. Hanley pages 93.e1-93.e7 Abstract | Full Text | Full-Text PDF (172 KB)
Electrophysiology
Right atrial pacing and the risk of postimplant atrial fibrillation in cardiac resynchronization therapy recipients, 26 October 2007 Evan Adelstein, Samir Saba pages 94-99 Abstract | Full Text | Full-Text PDF (370 KB)
A randomized comparison of amiodarone and class IC antiarrhythmic drugs to treat atrial fibrillation in patients paced for sinus node disease: The Prevention Investigation and Treatment: A Group for Observation and Research on Atrial arrhythmias (PITAGORA) trial, 19 November 2007 Michele Gulizia, Salvatore Mangiameli, Serafino Orazi, Giacomo Chiarandà, Guglielmo Piccione, Nicolò Di Giovanni, Andrea Colletti, Orazio Pensabene, Francesco Lisi, Ludovico Vasquez, Andrea Grammatico, Giuseppe Boriani, on behalf of PITAGORA Study Investigators pages 100.e1-100.e9 Abstract | Full Text | Full-Text PDF (331 KB)
Interventional Cardiology
Comparison of vascular response to zotarolimus-eluting stent versus sirolimus-eluting stent: Intravascular ultrasound results from ENDEAVOR III, 17 September 2007 Akiyoshi Miyazawa, Junya Ako, Yoichiro Hongo, Seung-Ho Hur, Ichizo Tsujino, Brian K. Courtney, Ali H.M. Hassan, David E. Kandzari, Yasuhiro Honda, Peter J. Fitzgerald, for the ENDEAVOR III Investigators pages 108-113 Abstract | Full Text | Full-Text PDF (399 KB)
A randomized, double-blind, placebo-controlled study of the safety and efficacy of intravenous MCC-135 as an adjunct to primary percutaneous coronary intervention in patients with acute myocardial infarction: Evaluation of MCC-135 for left ventricular salvage in acute myocardial infarction (EVOLVE), 12 October 2007 Ik-Kyung Jang, Neil J. Weissman, Michael H. Picard, Michael R. Zile, Veronica Pettigrew, Steven Shen, Jun Tatsuno, Mark G. Hibberd, Dan Tzivoni, Frans J. Th. Wackers, the EVOLVE Investigators pages 113.e1-113.e8 Abstract | Full Text | Full-Text PDF (264 KB)
Risk-adjusted sequential probability ratio test control chart methods for monitoring operator and institutional mortality rates in interventional cardiology, 08 October 2007 Michael E. Matheny, Lucila Ohno-Machado, Frederic S. Resnic pages 114-120 Abstract | Full Text | Full-Text PDF (430 KB)
Guideline adjudicated fibrinolytic failure: Incidence, findings, and management in a contemporary clinical trial, 08 October 2007 Christopher E. Buller, Robert C. Welsh, Cynthia M. Westerhout, John G. Webb, Blair O'Neill, Richard Gallo, Paul W. Armstrong pages 121-127 Abstract | Full Text | Full-Text PDF (279 KB)
Use of endothelial progenitor cell capture stent (Genous Bio-Engineered R Stent) during primary percutaneous coronary intervention in acute myocardial infarction: Intermediate- to long-term clinical follow-up, 23 November 2007 Melissa Co, Edgar Tay, Chi Hang Lee, Kian Keong Poh, Adrian Low, Jimmy Lim, Ing Han Lim, Yean Teng Lim, Huay Cheem Tan pages 128-132 Abstract | Full Text | Full-Text PDF (93 KB)
Effects of pretreatment with clopidogrel on nonemergent percutaneous coronary intervention after fibrinolytic administration for ST-segment elevation myocardial infarction: A Clopidogrel as Adjunctive Reperfusion Therapy–Thrombolysis in Myocardial Infarction (CLARITY-TIMI) 28 study, 19 November 2007 C. Michael Gibson, Sabina A. Murphy, Yuri B. Pride, Ajay J. Kirtane, Julian M. Aroesty, Erica B. Stein, Lauren N. Ciaglo, Matthew C. Southard, Marc S. Sabatine, Christopher P. Cannon, Eugene Braunwald, for the TIMI Study Group pages 133-139 Abstract | Full Text | Full-Text PDF (182 KB)
Culprit-only or multivessel revascularization in patients with acute coronary syndromes: An American College of Cardiology National Cardiovascular Database Registry report Sorin J. Brener, Sarah Milford-Beland, Matthew T. Roe, Deepak L. Bhatt, William S. Weintraub, Ralph G. Brindis pages 140-146 Abstract | Full Text | Full-Text PDF (242 KB)
Imaging and Diagnostic Testing
Role of magnetic resonance imaging in arrhythmogenic right ventricular dysplasia: Insights from the North American arrhythmogenic right ventricular dysplasia (ARVD/C) study, 17 September 2007 Harikrishna Tandri, Robson Macedo, Hugh Calkins, Frank Marcus, David Cannom, Melvin Scheinman, James Daubert, Mark Estes, David Wilber, Mario Talajic, Henry Duff, Andrew Krahn, Michael Sweeney, Hasan Garan, David A. Bluemke, for the Multidisciplinary Study of Right Ventricular Dysplasia Investigators pages 147-153 Abstract | Full Text | Full-Text PDF (282 KB)
Predictive value of coronary calcifications for future cardiac events in asymptomatic individuals, 08 October 2007 Alexander Becker, Alexander Leber, Christoph Becker, Andreas Knez pages 154-160 Abstract | Full Text | Full-Text PDF (304 KB)
Failure of digital echocardiography to accurately diagnose intracardiac shunts, 19 November 2007 Hind W. Rahmouni, Martin G. Keane, Frank E. Silvestry, Martin G. St. John Sutton, Victor A. Ferrari, Craig H. Scott, Susan E. Wiegers pages 161-165 Abstract | Full Text | Full-Text PDF (147 KB)
Pediatrics
Pulmonary vascular input impedance is a combined measure of pulmonary vascular resistance and stiffness and predicts clinical outcomes better than pulmonary vascular resistance alone in pediatric patients with pulmonary hypertension, 28 September 2007 Kendall S. Hunter, Po-Feng Lee, Craig J. Lanning, D. Dunbar Ivy, K. Scott Kirby, Lori R. Claussen, K. Chen Chan, Robin Shandas pages 166-174 Abstract | Full Text | Full-Text PDF (803 KB)
Prevention and Rehabilitation
Interactions of wine drinking with omega-3 fatty acids in patients with coronary heart disease: A fish-like effect of moderate wine drinking, 28 September 2007 Michel de Lorgeril, Patricia Salen, Jean-Louis Martin, François Boucher, Joël de Leiris pages 175-181 Abstract | Full Text | Full-Text PDF (119 KB)
Valvular and Congenital Heart Disease
Effect of pulmonary artery angioplasty on exercise function after repair of tetralogy of Fallot, 08 October 2007 Nicole J. Sutton, Lynn Peng, James E. Lock, Peter Lang, Gerald R. Marx, Tracy J. Curran, Julie-Ann O'Neill, Sarah T. Picard, Jonathan Rhodes pages 182-186 Abstract | Full Text | Full-Text PDF (212 KB)
Increased central aortic stiffness and left ventricular mass in normotensive young subjects after successful coarctation repair, 19 November 2007 Phalla Ou, David S. Celermajer, Odile Jolivet, Fanny Buyens, Alain Herment, Daniel Sidi, Damien Bonnet, Elie Mousseaux pages 187-193 Abstract | Full Text | Full-Text PDF (286 KB)
Letter to the Editor
Letter to the Editor Alberto Morales Salinas, Greter Lopez Morales, Ramiro Ramos Ramirez page e1 Full Text | Full-Text PDF (46 KB)
Frontmatter
Table of Contents pages A1-A4 Full-Text PDF (72 KB)
Editorial Board page A5 Full-Text PDF (33 KB)
Information for Authors pages A6-A7 Full-Text PDF (74 KB)
Information for Readers page A8 Full-Text PDF (44 KB)
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