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Editorial
The vulnerable endothelium: Priming the vascular endothelium for thrombosis with unfractionated heparin: Biologic plausibility for observations from the Superior Yield of the New Strategy of Enoxaparin, Revascularization and GlYcoprotein IIb/IIIa Inhibitors (SYNERGY) trial Richard C. Becker pages 189-192 Full Text | Full-Text PDF (79 KB)
Curriculum in Cardiology
Biopsychosocial experiences of adults with congenital heart disease: Review of the literature Adrienne H. Kovacs, Samuel F. Sears, Arwa S. Saidi pages 193-201 Abstract | Full Text | Full-Text PDF (167 KB)
Trial Design
Methodological design for economic evaluation in Public Access Defibrillation (PAD) trial Graham Nichol, George Arthur Wells, Karen Kuntz, David Feeny, Will Longstreth, Brian Mahoney, Clay Mann, Ray Lucas, Mark Henry, Ella Huszti, Alice Birnbaum pages 202-208 Abstract | Full Text | Full-Text PDF (302 KB)
Clinical Investigations
Acute Ischemic Heart Disease
Blood glucose: A strong risk factor for mortality in nondiabetic patients with cardiovascular disease Sidney C. Port, Mark O. Goodarzi, Noel G. Boyle, Robert I. Jennrich pages 209-214 Abstract | Full Text | Full-Text PDF (172 KB)
Left ventricular ejection fraction to predict early mortality in patients with non–ST-segment elevation acute coronary syndromes Xavier Bosch, Pierre Théroux pages 215-220 Abstract | Full Text | Full-Text PDF (132 KB)
A randomized trial comparing clopidogrel versus ticlopidine therapy in patients undergoing infarct artery stenting for acute myocardial infarction with abciximab as adjunctive therapy Guido Parodi, Roberto Sciagrà, Angela Migliorini, Gentian Memisha, Guia Moschi, Renato Valenti, Alberto Pupi, David Antoniucci pages 220.e1-220.e5 Abstract | Full Text | Full-Text PDF (93 KB)
Heart disease epidemic in Pakistan: Women and men at equal risk Tazeen H. Jafar, Fahim H. Jafary, Saleem Jessani, Nish Chaturvedi pages 221-226 Abstract | Full Text | Full-Text PDF (114 KB)
Association between cardiac troponin T elevation and angioscopic morphology of culprit lesion in patients with non–ST-segment elevation acute coronary syndrome Tomohito Ohtani, Yasunori Ueda, Masahiko Shimizu, Isamu Mizote, Atushi Hirayama, Masatsugu Hori, Kazuhisa Kodama pages 227-233 Abstract | Full Text | Full-Text PDF (252 KB)
Symptoms and type of symptom onset in acute coronary syndrome in relation to ST elevation, sex, age, and a history of diabetes Marie Thuresson, Marianne Berglin Jarlöv, Bertil Lindahl, Leif Svensson, Crister Zedigh, Johan Herlitz pages 234-242 Abstract | Full Text | Full-Text PDF (128 KB)
Genetics
Candidate gene susceptibility variants predict intermediate end points but not angiographic coronary artery disease Bryant M. Whiting, Jeffrey L. Anderson, Joseph B. Muhlestein, Benjamin D. Horne, Tami L. Bair, Robert R. Pearson, John F. Carlquist, for the Intermountain Heart Collaborative (IHC) Study Group. pages 243-250 Abstract | Full Text | Full-Text PDF (275 KB)
Electrophysiology
Reproducibility of nitrate-stimulated tilt testing in patients with suspected vasovagal syncope and a healthy control group Arnaud J.J. Aerts, Paul Dendale, Pierre Block, Willem R.M. Dassen pages 251-256 Abstract | Full Text | Full-Text PDF (165 KB)
Congestive Heart Failure
Effect of angiotensin-converting enzyme or vasopeptidase inhibition on ventricular size and function in patients with heart failure: The Omapatrilat Versus Enalapril Randomized Trial of Utility in Reducing Events (OVERTURE) echocardiographic study Scott D. Solomon, Hicham Skali, Mikhail Bourgoun, James Fang, Jalal K. Ghali, Michel Martelet, Dariusz Wojciechowski, Baiba Ansmite, Janis Skards, Toivo Laks, David Henry, Milton Packer, Marc A. Pfeffer, for the OVERTURE Investigators pages 257-262 Abstract | Full Text | Full-Text PDF (114 KB)
Impact of pregnancy-related heart failure on humoral immunity: Clinical relevance of G3-subclass immunoglobulins in peripartum cardiomyopathy Rahat S. Warraich, Karen Sliwa, Albertino Damasceno, Robert Carraway, Bruce Sundrom, Gulnaz Arif, Raffique Essop, Aftab Ansari, James Fett, Magdi Yacoub pages 263-269 Abstract | Full Text | Full-Text PDF (130 KB)
Peripheral Vascular Disease
Walking may be related to less vascular stiffness in the Activity Counseling Trial (ACT) Richard J. Havlik, Caroline L. Phillips, Dwight B. Brock, Kurt Lohman, William Haskell, Peter Snell, Mary O'Toole, Paul Ribisl, Peter Vaitkevicius, Harold A. Spurgeon, Edward G. Lakatta, Paul Pullen pages 270-275 Abstract | Full Text | Full-Text PDF (147 KB)
Patterns of inflammation associated with peripheral arterial disease: The InCHIANTI study Mary McGrae McDermott, Jack M. Guralnik, Annamaria Corsi, Monique Albay, Claudio Macchi, Stefania Bandinelli, Luigi Ferrucci pages 276-281 Abstract | Full Text | Full-Text PDF (145 KB)
Prevention and Rehabilitation
The benefit of cholesterol-lowering medications after coronary revascularization: A population study James M. Brophy, Paul Brassard, Chantal Bourgault pages 282-286 Abstract | Full Text | Full-Text PDF (100 KB)
Plasma low-density lipoprotein reduction and structural effects on coronary atherosclerotic plaques by atorvastatin as clinically assessed with intravascular ultrasound radio-frequency signal analysis: A randomized prospective study Masaki Yokoyama, Nobuyuki Komiyama, Brian K. Courtney, Takashi Nakayama, Susumu Namikawa, Nehiro Kuriyama, Tomomi Koizumi, Mizuo Nameki, Peter J. Fitzgerald, Issei Komuro pages 287.e1-287.e7 Abstract | Full Text | Full-Text PDF (232 KB)
Surgery
Left Atrial Appendage Occlusion Study (LAAOS): Results of a randomized controlled pilot study of left atrial appendage occlusion during coronary bypass surgery in patients at risk for stroke Jeff S. Healey, Eugene Crystal, Andre Lamy, Kevin Teoh, Lloyd Semelhago, Stefan H. Hohnloser, Irene Cybulsky, Labib Abouzahr, Corey Sawchuck, Sandra Carroll, Carlos Morillo, Peter Kleine, Victor Chu, Eva Lonn, Stuart J. Connolly pages 288-293 Abstract | Full Text | Full-Text PDF (206 KB)
Valvular and Congenital Heart Disease
Regional myocardial velocities and isovolumic contraction acceleration before and after device closure of atrial septal defects: A color tissue Doppler study Linda B. Pauliks, Kak-Chen Chan, Dennis Chang, Scott K. Kirby, Loralee Logan, Curt G. DeGroff, Mark M. Boucek, Lilliam M. Valdes-Cruz pages 294-301 Abstract | Full Text | Full-Text PDF (315 KB)
Impact of vitamin E and C supplementation on serum adhesion molecules in chronic degenerative aortic stenosis: A randomized controlled trial Muhammad Tahir, Brendan Foley, Gordon Pate, Peter Crean, David Moore, Nuala McCarroll, Michael Walsh pages 302-306 Abstract | Full Text | Full-Text PDF (102 KB)
Imaging and Diagnostic Testing
Can we reliably predict long-term mortality after exercise testing? An external validation Barbara Hesse, Anthony Morise, Claire E. Pothier, Eugene H. Blackstone, Michael S. Lauer pages 307-314 Abstract | Full Text | Full-Text PDF (381 KB)
Coronary venous imaging with electron beam computed tomographic angiography: Three-dimensional mapping and relationship with coronary arteries Songshou Mao, Jerold S. Shinbane, Marc J. Girsky, Janis Child, Sivi Carson, Ronald J. Oudiz, Matthew J. Budoff pages 315-322 Abstract | Full Text | Full-Text PDF (533 KB)
Outcomes, Health Policy, and Managed Care
Resource use, costs, and quality of life among patients in the multinational Valsartan in Acute Myocardial Infarction Trial (VALIANT) Shelby D. Reed, Jasmina I. Radeva, Kevin P. Weinfurt, John J.V. McMurray, Marc A. Pfeffer, Eric J. Velazquez, Jennifer S. Allsbrook, Leah E. Masselink, Mary Ann Sellers, Robert M. Califf, Kevin A. Schulman, for the VALIANT Investigators pages 323-329 Abstract | Full Text | Full-Text PDF (390 KB)
Inhospital and 1-year mortality of patients who develop worsening renal function following acute ST-elevation myocardial infarction Alexander Goldberg, Haim Hammerman, Sirouch Petcherski, Alexander Zdorovyak, Sergey Yalonetsky, Michael Kapeliovich, Yoram Agmon, Walter Markiewicz, Doron Aronson pages 330-337 Abstract | Full Text | Full-Text PDF (148 KB)
Interventional Cardiology
Effect of lesion length on fractional flow reserve in intermediate coronary lesions David Brosh, Stuart T. Higano, Ryan J. Lennon, David R. Holmes, Amir Lerman pages 338-343 Abstract | Full Text | Full-Text PDF (126 KB)
Inflammatory response after intervention assessed by serial C-reactive protein measurements correlates with restenosis in patients treated with coronary stenting Alban Dibra, Julinda Mehilli, Siegmund Braun, Martin Hadamitzky, Hannsjörg Baum, Josef Dirschinger, Helmut Schühlen, Albert Schömig, Adnan Kastrati pages 344-350 Abstract | Full Text | Full-Text PDF (137 KB)
Sirolimus-eluting stent implantation and β-irradiation for the treatment of in-stent restenotic lesions: Comparison of underlying mechanisms of acute gain and late loss as assessed by volumetric intravascular ultrasound Thomas M. Schiele, Andreas König, Johannes Rieber, Isabelle Erhard, Marcus Leibig, Karl Theisen, Uwe Siebert, Volker Klauss pages 351-357 Abstract | Full Text | Full-Text PDF (146 KB)
Impact of smoking status on outcomes of primary coronary intervention for acute myocardial infarction—The smoker's paradox revisited Giora Weisz, David A. Cox, Eulogio Garcia, James E. Tcheng, John J. Griffin, Giulio Guagliumi, Thomas D. Stuckey, Barry D. Rutherford, Roxana Mehran, Eve Aymong, Alexandra Lansky, Cindy L. Grines, Gregg W. Stone pages 358-364 Abstract | Full Text | Full-Text PDF (123 KB)
Frontmatter
Table of Contents pages A1-A4 Full-Text PDF (151 KB)
Editorial Board page A5 Full-Text PDF (34 KB)
Instructions for Authors pages A6-A7 Full-Text PDF (74 KB)
Information for Readers page A8 Full-Text PDF (44 KB)
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