American Heart Journal
Volume 160, Issue 2 , Pages 264-271.e1 , August 2010

Diuretic dose and long-term outcomes in elderly patients with heart failure after hospitalization

  • Husam M. Abdel-Qadir, MD

      Affiliations

    • Department of Medicine, University of Toronto, Toronto, Ontario, Canada
    • ,
  • Jack V. Tu, MD, PhD

      Affiliations

    • Department of Medicine, University of Toronto, Toronto, Ontario, Canada
    • Institute for Clinical Evaluative Sciences, Toronto, Ontario, Canada
    • Division of Cardiology, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada
    • ,
  • Lingsong Yun, MSc

      Affiliations

    • Institute for Clinical Evaluative Sciences, Toronto, Ontario, Canada
    • ,
  • Peter C. Austin, PhD

      Affiliations

    • Institute for Clinical Evaluative Sciences, Toronto, Ontario, Canada
    • Dalla Lana School of Public Health, Toronto, Ontario, Canada
    • ,
  • Gary E. Newton, MD

      Affiliations

    • Department of Medicine, University of Toronto, Toronto, Ontario, Canada
    • Division of Cardiology, University Health Network, Toronto, Ontario, Canada
    • ,
  • Douglas S. Lee, MD, PhD

      Affiliations

    • Department of Medicine, University of Toronto, Toronto, Ontario, Canada
    • Institute for Clinical Evaluative Sciences, Toronto, Ontario, Canada
    • Division of Cardiology, University Health Network, Toronto, Ontario, Canada
    • Corresponding Author InformationReprint requests: Douglas S. Lee, MD, PhD, Institute for Clinical Evaluative Sciences, Rm G-106, 2075 Bayview Ave, Toronto, ON, Canada M4N 3M5.

Received 23 February 2010 ,Accepted 20 May 2010.

  • Image Result

    Patients included and excluded from the analysis.

    Patients included and excluded from the analysis.

  • Image Result

    A-C, Furosemide dose exposures as per outpatient pharmacare claims during the 5-year follow-up of patients stratified according to furosemide dose at discharge.

    A-C, Furosemide dose exposures as per outpatient pharmacare claims during the 5-year follow-up of patients stratified according to furosemide dose at discharge.

  • Image Result

    Adjusted Kaplan-Meier curves showing survival after hospital discharge, stratified by discharge dose category (log-rank, P < .001).

    Adjusted Kaplan-Meier curves showing survival after hospital discharge, stratified by discharge dose category (log-rank, P < .001).

  • Image Result

    Adjusted Kaplan-Meier curves showing survival free from HF hospitalizations after discharge, stratified by discharge dose category (log-rank, P < .001).

    Adjusted Kaplan-Meier curves showing survival free from HF hospitalizations after discharge, stratified by discharge dose category (log-rank, P < .001).

PII: S0002-8703(10)00438-2

doi: 10.1016/j.ahj.2010.05.032

American Heart Journal
Volume 160, Issue 2 , Pages 264-271.e1 , August 2010

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