American Heart Journal
Volume 159, Issue 3 , Pages 361-369.e4, March 2010

Rationale, design, and baseline data of the Japanese Primary Prevention Project (JPPP)—A randomized, open-label, controlled trial of aspirin versus no aspirin in patients with multiple risk factors for vascular events

  • Tamio Teramoto, MD, PhD

      Affiliations

    • Internal Medicine, Teikyo University School of Medicine, Tokyo, Japan
    • Corresponding Author InformationReprint requests: Tamio Teramoto, MD, PhD, Internal Medicine, Teikyo University School of Medicine, 2-11-1, Kaga, Itabashi-ku, Tokyo 173-8606, Japan.
  • ,
  • Kazuyuki Shimada, MD, PhD

      Affiliations

    • Department of Cardiology, Jichi Medical University Hospital, Tochigi, Japan
  • ,
  • Shinichiro Uchiyama, MD, PhD

      Affiliations

    • Department of Neurology, Tokyo Women's Medical University, Tokyo, Japan
  • ,
  • Masahiro Sugawara, MD

      Affiliations

    • Japan Physicians Association, Japan
  • ,
  • Yoshio Goto, MD, PhD

      Affiliations

    • Japan Physicians Association, Japan
  • ,
  • Nobuhiro Yamada, MD, PhD

      Affiliations

    • Tsukuba University Hospital, Institute of Clinical Medicine, University of Tsukuba, Ibaraki, Japan
  • ,
  • Shinichi Oikawa, MD, PhD

      Affiliations

    • Department of Medicine, Nippon Medical University, Tokyo, Japan
  • ,
  • Katsuyuki Ando, MD, PhD

      Affiliations

    • Division of Molecular Cardiovascular Metabolism, Department of Nephrology and Endocrinology, University of Tokyo Graduate School of Medicine, Tokyo, Japan
  • ,
  • Naoki Ishizuka, PhD

      Affiliations

    • Division of Preventive Medicine, Department of Community Health and Medicine, Research Institute, International Medical Center of Japan, Tokyo, Japan
  • ,
  • Tsutomu Yamazaki, MD, PhD

      Affiliations

    • Faculty of Medicine, Department of Clinical Epidemiology and Systems, Graduate School of Medicine, Center for Epidemiology and Preventive Medicine, The University of Tokyo, Tokyo, Japan
  • ,
  • Kenji Yokoyama, MD, PhD

      Affiliations

    • Division of Hematology, Department of Internal Medicine, Keio University School of Medicine, Tokyo, Japan
  • ,
  • Mitsuru Murata, MD, PhD

      Affiliations

    • Clinical Laboratory, Keio University School of Medicine, Tokyo, Japan
  • ,
  • Yasuo Ikeda, MD, PhD

      Affiliations

    • Major in Life Science and Medical Bioscience Graduate School of Advanced Science and Engineering, Waseda University, Tokyo, Japan

Received 22 May 2009; accepted 25 November 2009.

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 RCT#:NCT00225849.

PII: S0002-8703(09)00955-7

doi:10.1016/j.ahj.2009.11.030

American Heart Journal
Volume 159, Issue 3 , Pages 361-369.e4, March 2010