American Heart Journal
Volume 159, Issue 2 , Pages 183-189, February 2010

Primary care practices and determinants of optimal anticoagulation management in a collaborative care model

  • Kerby Maud Louis, BSc

      Affiliations

    • Biomedical Science Department, Faculty of Medicine, University of Montreal, Montreal, Canada
    • Research Team in Primary Care, Centre de santé et de services sociaux de Laval, Laval, Canada
  • ,
  • Josée Martineau, MSc, BCPS

      Affiliations

    • Centre de santé et de services sociaux de Laval, Laval, Canada
  • ,
  • Isabel Rodrigues, MD, MPH

      Affiliations

    • Centre de santé et de services sociaux de Laval, Laval, Canada
    • Faculty of Medicine, University of Montreal, Montreal, Canada
  • ,
  • Martine Fournier, MSc

      Affiliations

    • Research Center, Hôpital Charles LeMoyne, Longueuil, Canada
  • ,
  • Djamal Berbiche, PhD

      Affiliations

    • Research Team in Primary Care, Centre de santé et de services sociaux de Laval, Laval, Canada
  • ,
  • Normand Blais, MD, FRCP(C)

      Affiliations

    • Centre hospitalier de l'Université de Montréal–Hôpital Notre-Dame, Montreal, Canada
  • ,
  • Jeffrey Ginsberg, MD, FRCP(C)

      Affiliations

    • Department of Medicine, McMaster University, Hamilton, Canada
  • ,
  • Lucie Blais, PhD

      Affiliations

    • Faculty of Pharmacy, University of Montreal, Montreal, Canada
  • ,
  • Martine Montigny, MD, FRCP(C)

      Affiliations

    • Centre de santé et de services sociaux de Laval, Laval, Canada
  • ,
  • Sylvie Perreault, PhD

      Affiliations

    • Faculty of Pharmacy, University of Montreal, Montreal, Canada
  • ,
  • Marie-Claude Vanier, MSc

      Affiliations

    • Centre de santé et de services sociaux de Laval, Laval, Canada
    • Faculty of Pharmacy, University of Montreal, Montreal, Canada
    • Sanofi Aventis Endowment Research Chair in Ambulatory Pharmaceutical Care, University of Montreal and Centre de santé et de services sociaux de Laval, Laval, Canada
  • ,
  • Lyne Lalonde, PhD

      Affiliations

    • Research Team in Primary Care, Centre de santé et de services sociaux de Laval, Laval, Canada
    • Faculty of Pharmacy, University of Montreal, Montreal, Canada
    • Sanofi Aventis Endowment Research Chair in Ambulatory Pharmaceutical Care, University of Montreal and Centre de santé et de services sociaux de Laval, Laval, Canada
    • Corresponding Author InformationReprint requests: Lyne Lalonde, PhD, Research Team in Primary Care, Centre de santé et de services sociaux de Laval, Hôpital de la Cité-de-la-Santé, 1755 René-Laennec Blvd, Room D-S080, Laval, Quebec, Canada H7M 3L9.

Received 23 July 2009; accepted 18 November 2009.

Background

In a collaborative care model (CCM) for managing oral anticoagulant therapy, patients are followed at a pharmacist-managed anticoagulation service and, once stabilized, are transferred to their primary care physician. The objective of this study was to describe physicians' clinical practices and the practice characteristics associated with better international normalized ratio (INR) control in a CCM.

Methods

A telephone questionnaire about their practices was administered to 121 physicians exposed to a CCM. The physicians followed 121 patients for a mean of 14.5 weeks. The percentage of time within the exact INR target range was computed and dichotomized (≥ or < median time within target range). Determinants of better INR control were identified using logistic regression models.

Results

The survey revealed that, after discharge from the pharmacist-managed anticoagulation service, patients are followed mainly by physicians and their secretaries. Physicians do not often consult other health professionals. Few report using technological resources to obtain INR results (39.7%), document medical follow-up (6.6%), or detect drug (32.2%) and food (9.9%) interactions. The median percentage of time within the exact INR target range was 84%. Determinants of better INR control include using computerized support to monitor patients (odds ratio [OR] 9.16, 95% CI 1.77-47.4) and detect drug interactions (OR 3.49, 95% CI 1.71-7.10) and consulting specialists (OR 5.92, 95% CI 1.49-32.48).

Conclusions

Primary care physicians are poorly supported by technological and human resources to monitor patients on oral anticoagulant. Even in a CCM, interprofessional collaboration and better technological support may be associated with optimal INR control.

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 Institution where the study was conducted: Centre ambulatoire, Centre de santé et de services sociaux de Laval.

 An abstract of this study was published in the proceedings of the IXth World Conference on Clinical Pharmacology and Therapeutics (Quebec, Canada, July 2008).

PII: S0002-8703(09)00895-3

doi:10.1016/j.ahj.2009.11.015

American Heart Journal
Volume 159, Issue 2 , Pages 183-189, February 2010