American Heart Journal
Volume 159, Issue 2 , Pages 176-182 , February 2010

Randomized comparison between clinical evaluation plus N-terminal pro–B-type natriuretic peptide versus exercise testing for decision making in acute chest pain of uncertain origin

  • Juan Sanchis, MD

      Affiliations

    • Cardiology Department, University Clinic Hospital, University of Valencia, Valencia, Spain
    • Corresponding Author InformationReprint requests: Juan Sanchis, MD, Servei de Cardiologia, Hospital Clínic Universitari, Blasco Ibáñez 17, 46010 València, Spain.
    • ,
  • Xavier Bosch, MD

      Affiliations

    • Cardiology Department, Hospital Clínic, University of Barcelona, Barcelona, Spain
    • ,
  • Vicente Bodí, MD

      Affiliations

    • Cardiology Department, University Clinic Hospital, University of Valencia, Valencia, Spain
    • ,
  • Julio Núñez, MD

      Affiliations

    • Cardiology Department, University Clinic Hospital, University of Valencia, Valencia, Spain
    • ,
  • Ada Doltra, MD

      Affiliations

    • Cardiology Department, Hospital Clínic, University of Barcelona, Barcelona, Spain
    • ,
  • Magda Heras, MD

      Affiliations

    • Cardiology Department, Hospital Clínic, University of Barcelona, Barcelona, Spain
    • ,
  • Luis Mainar, MD

      Affiliations

    • Cardiology Department, University Clinic Hospital, University of Valencia, Valencia, Spain
    • ,
  • Enrique Santas, MD

      Affiliations

    • Cardiology Department, University Clinic Hospital, University of Valencia, Valencia, Spain
    • ,
  • Ernest Bragulat, MD

      Affiliations

    • Cardiology Department, Hospital Clínic, University of Barcelona, Barcelona, Spain
    • ,
  • Ana García-Alvarez, MD

      Affiliations

    • Cardiology Department, Hospital Clínic, University of Barcelona, Barcelona, Spain
    • ,
  • Arturo Carratalá, MD

      Affiliations

    • Clinical Biochemistry Department, University Clinic Hospital, Valencia, Spain
    • ,
  • Angel Llácer, MD

      Affiliations

    • Cardiology Department, University Clinic Hospital, University of Valencia, Valencia, Spain

Received 28 July 2009 ,Accepted 12 November 2009.

References 

  1. Sanchis J, Bodí V, Núñez J, et al. New risk score for patients with acute chest pain, non-ST-segment deviation, and normal troponin concentrations: a comparison with the TIMI risk score. J Am Coll Cardiol. 2005;46:443–449
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  8. Jeetley P, Burden L, Stoykova B, et al. Clinical and economic impact of stress echocardiography compared with exercise electrocardiography in patients with suspected acute coronary syndrome but negative troponin: a prospective randomized controlled study. Eur Heart J. 2007;28:204–211
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  11. Sanchis J, Bosch X, Bodí V, et al. Combination of clinical risk profile, early exercise testing and circulating biomarkers for evaluation of patients with acute chest pain, without ST-segment deviation or troponin elevation. Heart. 2008;94:311–315
  12. Geleijnse ML, Elhendy A, Kasprzak JD, et al. Safety and prognostic value of early dobutamine-atropine stress echocardiography in patients with spontaneous chest pain and a non-diagnostic electrocardiogram. Eur Heart J. 2000;21:397–406
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 RCT no. NCT00493844.

PII: S0002-8703(09)00882-5

doi: 10.1016/j.ahj.2009.11.010

American Heart Journal
Volume 159, Issue 2 , Pages 176-182 , February 2010

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