American Heart Journal
Volume 158, Issue 5 , Pages 769-776 , November 2009

Cardiac resynchronization therapy in patients with ischemic versus non-ischemic heart failure: Differential effect of optimizing interventricular pacing interval

  • Nina Ajmone Marsan, MD

      Affiliations

    • Departments of Cardiology, Leiden University Medical Center, Leiden, The Netherlands
  • ,
  • Gabe B. Bleeker, MD, PhD

      Affiliations

    • Departments of Cardiology, Leiden University Medical Center, Leiden, The Netherlands
  • ,
  • Rutger J. Van Bommel, MD

      Affiliations

    • Departments of Cardiology, Leiden University Medical Center, Leiden, The Netherlands
  • ,
  • Jan Willem Borleffs, MD

      Affiliations

    • Departments of Cardiology, Leiden University Medical Center, Leiden, The Netherlands
  • ,
  • Matteo Bertini, MD

      Affiliations

    • Departments of Cardiology, Leiden University Medical Center, Leiden, The Netherlands
  • ,
  • Eduard R. Holman, MD, PhD

      Affiliations

    • Departments of Cardiology, Leiden University Medical Center, Leiden, The Netherlands
  • ,
  • Ernst E. van der Wall, MD, PhD

      Affiliations

    • Departments of Cardiology, Leiden University Medical Center, Leiden, The Netherlands
    • Interuniversity Cardiology Institute of the Netherlands, Utrecht, The Netherlands
  • ,
  • Martin J. Schalij, MD, PhD

      Affiliations

    • Departments of Cardiology, Leiden University Medical Center, Leiden, The Netherlands
  • ,
  • Jeroen J. Bax, MD, PhD

      Affiliations

    • Departments of Cardiology, Leiden University Medical Center, Leiden, The Netherlands
    • Corresponding Author InformationReprint requests: Jeroen J. Bax, MD, PhD, Department of Cardiology, Leiden University Medical Center, Albinusdreef 2, 2333 ZA Leiden, The Netherlands.

Received 19 June 2009 ,Accepted 3 September 2009.

References 

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  2. Perego GB, Chianca R, Facchini M, et al. Simultaneous vs. sequential biventricular pacing in dilated cardiomyopathy: an acute hemodynamic study. Eur J Heart Fail. 2003;5:305–313
  3. Bordachar P, Lafitte S, Reuter S, et al. Echocardiographic parameters of ventricular dyssynchrony validation in patients with heart failure using sequential biventricular pacing. J Am Coll Cardiol. 2004;44:2157–2165
  4. Sogaard P, Egeblad H, Pedersen AK, et al. Sequential versus simultaneous biventricular resynchronization for severe heart failure: evaluation by tissue Doppler imaging. Circulation. 2002;106:2078–2084
  5. Porciani MC, Dondina C, Macioce R, et al. Echocardiographic examination of atrioventricular and interventricular delay optimization in cardiac resynchronization therapy. Am J Cardiol. 2005;95:1108–1110
  6. Vanderheyden M, De Backer T, Rivero-Ayerza M, et al. Tailored echocardiographic interventricular delay programming further optimizes left ventricular performance after cardiac resynchronization therapy. Heart Rhythm. 2005;2:1066–1072
  7. van Gelder BM, Bracke FA, Meijer A, et al. Effect of optimizing the VV interval on left ventricular contractility in cardiac resynchronization therapy. Am J Cardiol. 2004;93:1500–1503
  8. Vidal B, Sitges M, Marigliano A, et al. Optimizing the programation of cardiac resynchronization therapy devices in patients with heart failure and left bundle branch block. Am J Cardiol. 2007;100:1002–1006
  9. Leon AR, Abraham WT, Brozena S, et al. Cardiac resynchronization with sequential biventricular pacing for the treatment of moderate-to-severe heart failure. J Am Coll Cardiol. 2005;46:2298–2304
  10. Rao RK, Kumar UN, Schafer J, et al. Reduced ventricular volumes and improved systolic function with cardiac resynchronization therapy: a randomized trial comparing simultaneous biventricular pacing, sequential biventricular pacing, and left ventricular pacing. Circulation. 2007;115:2136–2144
  11. Boriani G, Muller CP, Seidl KH, et al. Randomized comparison of simultaneous biventricular stimulation versus optimized interventricular delay in cardiac resynchronization therapy. The Resynchronization for the HemodYnamic Treatment for Heart Failure Management II implantable cardioverter defibrillator (RHYTHM II ICD) study. Am Heart J. 2006;151:1050–1058
  12. Sutton MG, Plappert T, Hilpisch KE, et al. Sustained reverse left ventricular structural remodeling with cardiac resynchronization at one year is a function of etiology: quantitative Doppler echocardiographic evidence from the Multicenter InSync Randomized Clinical Evaluation (MIRACLE). Circulation. 2006;113:266–272
  13. Kedia N, Ng K, Apperson-Hansen C, et al. Usefulness of atrioventricular delay optimization using Doppler assessment of mitral inflow in patients undergoing cardiac resynchronization therapy. Am J Cardiol. 2006;98:780–785
  14. Bleeker GB, Bax JJ, Fung JW, et al. Clinical versus echocardiographic parameters to assess response to cardiac resynchronization therapy. Am J Cardiol. 2006;97:260–263
  15. Bax JJ, Bleeker GB, Marwick TH, et al. Left ventricular dyssynchrony predicts response and prognosis after cardiac resynchronization therapy. J Am Coll Cardiol. 2004;44:1834–1840
  16. Bleeker GB, Schalij MJ, Molhoek SG, et al. Relationship between QRS duration and left ventricular dyssynchrony in patients with end-stage heart failure. J Cardiovasc Electrophysiol. 2004;15:544–549
  17. Ypenburg C, Schalij MJ, Bleeker GB, et al. Impact of viability and scar tissue on response to cardiac resynchronization therapy in ischaemic heart failure patients. Eur Heart J. 2007;28:33–41
  18. Bax JJ, Abraham T, Barold SS, et al. Cardiac resynchronization therapy: Part 1 issues before device implantation. J Am Coll Cardiol. 2005;46:2153–2167
  19. Mullens W, Grimm RA, Verga T, et al. Insights from a cardiac resynchronization optimization clinic as part of a heart failure disease management program. J Am Coll Cardiol. 2009;53:765–773
  20. Bleeker GB, Kaandorp TA, Lamb HJ, et al. Effect of posterolateral scar tissue on clinical and echocardiographic improvement after cardiac resynchronization therapy. Circulation. 2006;113:969–976
  21. White JA, Yee R, Yuan X, et al. Delayed enhancement magnetic resonance imaging predicts response to cardiac resynchronization therapy in patients with intraventricular dyssynchrony. J Am Coll Cardiol. 2006;48:1953–1960

PII: S0002-8703(09)00721-2

doi: 10.1016/j.ahj.2009.09.004

American Heart Journal
Volume 158, Issue 5 , Pages 769-776 , November 2009