American Heart Journal
Volume 158, Issue 1 , Page e13 , July 2009

Response

References 

  1. Hacquebard M, Vandenbranden M, Malaisse WJ, et al. Vitamin E transfer from lipid emulsions to plasma lipoproteins: mediation by multiple mechanisms. Lipids. 2008;43:663–671
  2. Granot E, Tamir I, Deckelbaum RJ. Neutral lipid transfer protein does not regulate alpha-tocopherol transfer between human plasma lipoproteins. Lipids. 1988;23:17–21
  3. Desrumaux C, Deckert V, Athias A, et al. Plasma phospholipid transfer protein prevents vascular endothelium dysfunction by delivering alpha-tocopherol to endothelial cells. FASEB J. 1999;13:883–892
  4. Jiang XC, Tall AR, Qin S, et al. Phospholipid transfer protein deficiency protects circulating lipoproteins from oxidation due to the enhanced accumulation of vitamin E. J Biol Chem. 2002;277:31850–31856
  5. Bjelakovic G, Nikolova D, Gluud LL, et al. Mortality in randomized trials of antioxidant supplements for primary and secondary prevention: systematic review and meta-analysis. JAMA. 2007;297:842–857
  6. Barter PJ, Caulfield M, Eriksson M, et al. for the ILLUMINATE Investigators Effects of torcetrapib in patients at high risk for coronary events. N Engl J Med. 2007;357:2109–2122
  7. Krishna R, Anderson MS, Bergman AJ, et al. Effect of the cholesteryl ester transfer protein inhibitor, anacetrapib, on lipoproteins in patients with dyslipidaemia and on 24-h ambulatory blood pressure in healthy individuals: two double-blind, randomised placebo-controlled phase I studies. Lancet. 2007;370:1907–1914
  8. Forrest MJ, Bloomfield D, Briscoe RJ, et al. Torcetrapib-induced blood pressure elevation is independent of CETP inhibition and is accompanied by increased circulating levels of aldosterone. Br J Pharmacol. 2008;154:1465–1473
  9. Bloomfield D, Carlson GL, Sapre A, et al. Efficacy and safety of the cholesteryl ester transfer protein inhibitor anacetrapib as monotherapy and coadministered with atorvastatin in dyslipidemic patients. Am Heart J. 2009;157:352–360

PII: S0002-8703(09)00359-7

doi: 10.1016/j.ahj.2009.05.005

American Heart Journal
Volume 158, Issue 1 , Page e13 , July 2009