American Heart Journal
Volume 157, Issue 2 , Pages 334.e1-334.e8 , February 2009

Angiotensin-converting enzyme inhibition and novel cardiovascular risk biomarkers: Results from the Trial of Angiotensin Converting Enzyme Inhibition and Novel Cardiovascular Risk Factors (TRAIN) study

  • Matteo Cesari, MD, PhD

      Affiliations

    • Department of Aging and Geriatric Research, University of Florida-Institute on Aging, Gainesville, FL
    • Corresponding Author InformationReprint requests: Matteo Cesari, MD, PhD, Department of Aging and Geriatric Research, University of Florida-Institute on Aging, 210 East Mowry Road, Gainesville, FL 32611.
    • ,
  • Stephen B. Kritchevsky, PhD

      Affiliations

    • Section on Gerontology and Geriatric Medicine, J. Paul Sticht Center on Aging, Wake Forest University School of Medicine, Winston Salem, NC
    • ,
  • Hal H. Atkinson, MD

      Affiliations

    • Section on Gerontology and Geriatric Medicine, J. Paul Sticht Center on Aging, Wake Forest University School of Medicine, Winston Salem, NC
    • ,
  • Brenda W. Penninx, PhD

      Affiliations

    • Department of Psychiatry / EMGO Institute, VU University Medical Center, Amsterdam, The Netherlands
    • ,
  • Mauro Di Bari, MD, PhD

      Affiliations

    • Department of Critical Care Medicine and Surgery, University of Florence, Florence, Italy
    • ,
  • Russell P. Tracy, PhD

      Affiliations

    • Laboratory for Clinical Biochemistry Research, University of Vermont College of Medicine, Burlington, VT
    • ,
  • Marco Pahor, MD

      Affiliations

    • Department of Aging and Geriatric Research, University of Florida-Institute on Aging, Gainesville, FL

Received 23 May 2008 ,Accepted 23 October 2008.

  • Image Result

    Design of the Trial of Angiotensin Converting Enzyme Inhibition and Novel Cardiovascular Risk Factors (TRAIN) study.

    Design of the Trial of Angiotensin Converting Enzyme Inhibition and Novel Cardiovascular Risk Factors (TRAIN) study.

 Clinical trial registration no. NCT0051389.

 The TRAIN study is National Institutes of Health–funded project (NIH grant R01-HL68901). The TRAIN study was also (partially) supported by the University of Florida Claude D. Pepper Older Americans Independence Center (NIH grant 1P30-AG028740), Wake Forest University Claude D. Pepper Older Americans Independence Center (NIH grant 5P30-AG021332), and the Wake Forest University General Clinical Research Center (NIH grant M01-RR07122).

 Fosinopril was donated by Bristol-Myers Squibb (New York, NY).

PII: S0002-8703(08)00918-6

doi: 10.1016/j.ahj.2008.10.026

American Heart Journal
Volume 157, Issue 2 , Pages 334.e1-334.e8 , February 2009

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