Clinical InvestigationInterventional CardiologyGender differences among patients with acute coronary syndromes undergoing percutaneous coronary intervention in the American College of Cardiology-National Cardiovascular Data Registry (ACC-NCDR)
Section snippets
Data collection
The American College of Cardiolology-National Cardiovascular Data Registry (ACC-NCDR) is a national cardiac catheterization laboratory registry. Hospitals performing cardiac catheterization and PCI procedures voluntarily participate in data collection. Data are collected retrospectively or concurrently and represent consecutive patients treated at each institution. A standardized set of data elements and definitions, systematic data entry, and transmission procedures are used to ensure rigorous
Clinical characteristics
A total of 199,690 patients, 131,664 men and 68,026 women, met the inclusion criteria for this study. Of these, 157,652 patients presented with UA/NSTEMI and 42,038 patients presented with STEMI. A significant difference in presenting diagnosis based on gender was observed where a higher proportion of women presented with UA/NSTEMI than men (82% of women vs 77% of men, P < .01). Women were older than men whether presenting with UA/NSTEMI or STEMI (Table I). Most patients were white (87%).
In
Discussion
The ACC-NCDR reflects treatment patterns across the United States and affords an analysis of contemporary management of ACS patients undergoing PCI in the DES era. Our results demonstrate gender differences in clinical presentation, angiographic features, administration of antiplatelet therapies, and higher procedural complications in women with ACS who had a PCI during admission. Many of these differences persisted despite adjustment for baseline risk factors.
Women present significantly more
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Dr. W. Douglas Weaver served as guest editor for this manuscript.