American Heart Journal
Volume 156, Issue 4 , Pages 682-688, October 2008

The economic returns of pediatric clinical trials of antihypertensive drugs

  • Carissa M. Baker-Smith, MD, MS

      Affiliations

    • Department of Pediatrics, Duke University Medical Center, Durham, NC
    • ,
  • Daniel K. Benjamin Jr, MD, PhD

      Affiliations

    • Department of Pediatrics, Duke University Medical Center, Durham, NC
    • Duke Clinical Research Institute, Durham, NC
    • ,
  • Henry G. Grabowski, PhD

      Affiliations

    • Department of Economics, Duke University, Durham, NC
    • ,
  • Elizabeth D. Reid, BA

      Affiliations

    • Duke Clinical Research Institute, Durham, NC
    • ,
  • Barry Mangum, PharmD

      Affiliations

    • Duke Clinical Research Institute, Durham, NC
    • ,
  • John V. Goldsmith, PhD

      Affiliations

    • US Food and Drug Administration, Rockville, MD
    • ,
  • M. Dianne Murphy, MD

      Affiliations

    • US Food and Drug Administration, Rockville, MD
    • ,
  • Rex Edwards, BS

      Affiliations

    • Duke Clinical Research Institute, Durham, NC
    • ,
  • Eric L. Eisenstein, DBA

      Affiliations

    • Duke Clinical Research Institute, Durham, NC
    • ,
  • Jessica Sun, MD

      Affiliations

    • Department of Pediatrics, Duke University Medical Center, Durham, NC
    • ,
  • Robert M. Califf, MD

      Affiliations

    • Duke Clinical Research Institute, Durham, NC
    • ,
  • Jennifer S. Li, MD, MHS

      Affiliations

    • Department of Pediatrics, Duke University Medical Center, Durham, NC
    • Duke Clinical Research Institute, Durham, NC
    • Corresponding Author InformationReprint requests: Jennifer S. Li, MD, MHS, Duke Clinical Research Institute, PO Box 17969, Durham, NC 27705.

Received 28 February 2008; accepted 2 May 2008.

To access this article, please choose from the options below

Login to an existing account or Register a new account.

  • Purchase this article for 31.50 USD (You must login/register to purchase this article)

    Online access for 24 hours. The PDF version can be downloaded as your permanent record.

  • Subscribe to this title

    Get unlimited online access to this article and all other articles in this title 24/7 for one year.

  • Claim access now

    For current subscribers with Society Membership or Account Number.

  • Visit SciVerse ScienceDirect to see if you have access via your institution.

 Dr Baker-Smith is funded by National Institutes of Health (Bethesda, MD) T32 grant (HL069749-04). Drs Li and Benjamin received support from the National Institute of Child Health and Human Development (NICHD) (Rockville, MD) 1U10-HD45962-04 and the US Food and Drug Administration (Rockville, MD). Drs Benjamin, Li, and Califf received support from 1UL1RR024128-01.

 The views expressed are those of the authors. No official endorsement by the US Food and Drug Administration is provided or should be inferred.

 The Duke Clinical Research Institute (Durham, NC) was the coordinating center for 2 of the trials of drugs mentioned in this study.

PII: S0002-8703(08)00351-7

doi:10.1016/j.ahj.2008.05.001

American Heart Journal
Volume 156, Issue 4 , Pages 682-688, October 2008

Article Tools

* Image Usage & Resolution