American Heart Journal
Volume 156, Issue 2 , Pages 329-335 , August 2008

Predictive power of systolic function and congestive heart failure in patients with patients admitted for chest pain without ST elevation in the troponin era

  • Michael C. Kontos, MD

      Affiliations

    • Cardiology Division, Department of Internal Medicine, Virginia Commonwealth University, Richmond, VA
    • Department of Emergency Medicine, Virginia Commonwealth University, Richmond, VA
    • Department of Radiology, Virginia Commonwealth University, Richmond, VA
    • Corresponding Author InformationReprint requests: Michael C. Kontos, MD, Room 285 Gateway Building 2nd floor, PO Box 980051, Medical College of Virginia, 1200 E Marshall St, Richmond, VA 23298-0051.
  • ,
  • Sameer Jamal, MD

      Affiliations

    • Cardiology Division, Department of Internal Medicine, Virginia Commonwealth University, Richmond, VA
  • ,
  • James L. Tatum, MD

      Affiliations

    • Department of Cancer Imaging Program, NCI, National Institutes of Health, Bethesda, MD
  • ,
  • Joseph P. Ornato, MD

      Affiliations

    • Department of Emergency Medicine, Virginia Commonwealth University, Richmond, VA
  • ,
  • Robert L. Jesse, MD, PhD

      Affiliations

    • Cardiology Division, Department of Internal Medicine, Virginia Commonwealth University, Richmond, VA

Received 5 September 2007 ,Accepted 11 March 2008.

References 

  1. Risk stratification and survival after myocardial infarction. N Engl J Med. 1983;309:331–336
  2. Nicolosi GL, Latini R, Marino P, et al. The prognostic value of predischarge quantitative two-dimensional echocardiographic measurements and the effects of early lisinopril treatment on left ventricular structure and function after acute myocardial infarction in the GISSI-3 Trial. Gruppo Italiano per lo Studio della Sopravvivenza nell'Infarto Miocardico. Eur Heart J. 1996;17:1646–1656
  3. Krumholz HM, Chen J, Chen YT, et al. Predicting one-year mortality among elderly survivors of hospitalization for an acute myocardial infarction: results from the Cooperative Cardiovascular Project. J Am Coll Cardiol. 2001;38:453–459
  4. Hasdai D, Topol EJ, Kilaru R, et al. Frequency, patient characteristics, and outcomes of mild-to-moderate heart failure complicating ST-segment elevation acute myocardial infarction: lessons from 4 international fibrinolytic therapy trials. Am Heart J. 2003;145:73–79
  5. Khot UN, Jia G, Moliterno DJ, et al. Prognostic importance of physical examination for heart failure in non-ST-elevation acute coronary syndromes: the enduring value of Killip classification. JAMA. 2003;290:2174–2181
  6. Boersma E, Pieper KS, Steyerberg EW, et al. Predictors of outcome in patients with acute coronary syndromes without persistent ST-segment elevation. Results from an international trial of 9461 patients. Circulation. 2000;101:2557–2567
  7. Tatum JL, Jesse RL, Kontos MC, et al. Comprehensive strategy for the evaluation and triage of the chest pain patient. Ann Emerg Med. 1997;29:116–123
  8. Germano G, Kiat H, Kavanagh PB, et al. Automatic quantification of ejection fraction from gated myocardial perfusion SPECT. J Nucl Med. 1995;36:2138–2147
  9. Kontos MC, Kurdziel K, McQueen R, et al. Comparison of 2-dimensional echocardiography and myocardial perfusion imaging for diagnosing myocardial infarction in emergency department patients. Am Heart J. 2002;143:659–667
  10. Levey AS, Coresh J, Balk E, et al. National Kidney Foundation practice guidelines for chronic kidney disease: evaluation, classification, and stratification. Ann Intern Med. 2003;139:137–147
  11. Kontos MC, Shah R, Fritz LM, et al. Implication of different cardiac troponin I levels for clinical outcomes and prognosis of acute chest pain patients. J Am Coll Cardiol. 2004;43:958–965
  12. Alpert JS, Thygesen K, Bassand JP, et al. Myocardial infarction redefined—a consensus document of the Joint European Society of Cardiology/American College of Cardiology Committee for the Redefinition of Myocardial Infarction. J Am Coll Cardiol. 2000;36:959–969
  13. Killip T, Kimball JT. Treatment of myocardial infarction in a coronary care unit. A two year experience with 250 patients. Am J Cardiol. 1967;20:457–464
  14. Lee KL, Woodlief LH, Topol EJ, et al. Predictors of 30-day mortality in the era of reperfusion for acute myocardial infarction. Results from an international trial of 41,021 patients. GUSTO-I Investigators. Circulation. 1995;91:1659–1668
  15. Steg PG, Dabbous OH, Feldman LJ, et al. Determinants and prognostic impact of heart failure complicating acute coronary syndromes: observations from the Global Registry of Acute Coronary Events (GRACE). Circulation. 2004;109:494–499
  16. Spencer FA, Meyer TE, Gore JM, et al. Heterogeneity in the management and outcomes of patients with acute myocardial infarction complicated by heart failure: the National Registry of Myocardial Infarction. Circulation. 2002;105:2605–2610
  17. Bosch X, Theroux P. Left ventricular ejection fraction to predict early mortality in patients with non-ST-segment elevation acute coronary syndromes. Am Heart J. 2005;150:215–220
  18. Effect of enalapril on mortality and the development of heart failure in asymptomatic patients with reduced left ventricular ejection fractions. The SOLVD Investigators. N Engl J Med. 1992;327:685–691
  19. Yusuf S, Pfeffer MA, Swedberg K, et al. Effects of candesartan in patients with chronic heart failure and preserved left-ventricular ejection fraction: the CHARM-Preserved Trial. Lancet. 2003;362:777–781
  20. Roe MT, Chen AY, Riba AL, et al. Impact of congestive heart failure in patients with non-ST-segment elevation acute coronary syndromes. Am J Cardiol. 2006;97:1707–1712
  21. Velazquez EJ, Francis GS, Armstrong PW, et al. An international perspective on heart failure and left ventricular systolic dysfunction complicating myocardial infarction: the VALIANT registry. Eur Heart J. 2004;25:1911–1919
  22. Bennett KM, Hernandez AF, Chen AY, et al. Heart failure with preserved left ventricular systolic function among patients with non–ST-segment elevation acute coronary syndromes. Am J Cardiol. 2007;99:1351–1356
  23. Gottlieb S, Moss AJ, McDermott M, et al. Interrelation of left ventricular ejection fraction, pulmonary congestion and outcome in acute myocardial infarction. Am J Cardiol. 1992;69:977–984
  24. Hasdai D, Behar S, Wallentin L, et al. A prospective survey of the characteristics, treatments and outcomes of patients with acute coronary syndromes in Europe and the Mediterranean basin; the Euro Heart Survey of Acute Coronary Syndromes (Euro Heart Survey ACS). Eur Heart J. 2002;23:1190–1201
  25. Nicod P, Gilpin E, Dittrich H, et al. Influence on prognosis and morbidity of left ventricular ejection fraction with and without signs of left ventricular failure after acute myocardial infarction. Am J Cardiol. 1988;61:1165–1171
  26. Matetzky S, Friemark D, Feinberg MS, et al. Acute myocardial infarction with isolated ST-segment elevation in posterior chest leads V7-9. J Am Coll Cardiol. 1999;34:748–753
  27. Antman EM, Cohen M, Bernink PJLM, et al. The TIMI risk score for unstable angina/non–ST elevation MI. A method for prognostication and therapeutic decision making. JAMA. 2000;284:835–842
  28. Granger CB, Goldberg RJ, Dabbous O, et al. Predictors of hospital mortality in the global registry of acute coronary events. Arch Intern Med. 2003;163:2345–2353
  29. Eagle KA, Lim MJ, Dabbous OH, et al. A validated prediction model for all forms of acute coronary syndrome: estimating the risk of 6-month postdischarge death in an international registry. JAMA. 2004;291:2727–2733
  30. Gibson CM, Dumaine RL, Gelfand EV, et al. Association of glomerular filtration rate on presentation with subsequent mortality in non–ST-segment elevation acute coronary syndrome; observations in 13,307 patients in five TIMI trials. Eur Heart J. 2004;25:1998–2005
  31. Apple FS, Murakami M, Panteghini M, et al. International survey on the use of cardiac markers. Clin Chem. 2001;47:587–588
  32. Spencer FA, Moscucci M, Granger CB, et al. Does comorbidity account for the excess mortality in patients with major bleeding in acute myocardial infarction?. Circulation. 2007;116:2793–2801

PII: S0002-8703(08)00218-4

doi: 10.1016/j.ahj.2008.03.013

American Heart Journal
Volume 156, Issue 2 , Pages 329-335 , August 2008