American Heart Journal
Volume 155, Issue 1 , Pages 49-55, January 2008

Myeloid-related protein 8/14 and the risk of cardiovascular death or myocardial infarction after an acute coronary syndrome in the Pravastatin or Atorvastatin Evaluation and Infection Theraphy: Thrombolysis in Myocardial Infarction (PROVE IT-TIMI 22) trial

  • David A. Morrow, MD, MPH

      Affiliations

    • Thrombolysis in Myocardial Infarction (TIMI) Study Group, Brigham and Women's Hospital, Boston, MA
    • Cardiovascular Division, Brigham and Women's Hospital, Boston, MA
    • Department of Medicine, Harvard Medical School, Boston, MA
    • These authors contributed equally to this work.
    • Corresponding Author InformationReprint requests: David A. Morrow, MD, MPH, is to be contacted at TIMI Study Group/Cardiovascular Division, Brigham and Women's Hospital, 75 Francis Street, Boston, MA 02115. Daniel I. Simon, MD, Division of Cardiovascular Medicine, University Hospitals Case Medical Center, 11100 Euclid Avenue Lakeside 3001, Cleveland, OH 44106.
    • ,
  • Yunmei Wang, PhD

      Affiliations

    • Division of Cardiovascular Medicine, University Hospitals Case Medical Center, Case Western Reserve University School of Medicine, Cleveland, OH
    • These authors contributed equally to this work.
    • ,
  • Kevin Croce, MD, PhD

      Affiliations

    • Cardiovascular Division, Brigham and Women's Hospital, Boston, MA
    • ,
  • Masashi Sakuma, MD

      Affiliations

    • Division of Cardiovascular Medicine, University Hospitals Case Medical Center, Case Western Reserve University School of Medicine, Cleveland, OH
    • ,
  • Marc S. Sabatine, MD, MPH

      Affiliations

    • Thrombolysis in Myocardial Infarction (TIMI) Study Group, Brigham and Women's Hospital, Boston, MA
    • Cardiovascular Division, Brigham and Women's Hospital, Boston, MA
    • Donald W. Reynolds Center for Clinical Cardiovascular Research, Brigham and Women's Hospital, Women's Hospital, Boston, MA
    • Department of Medicine, Harvard Medical School, Boston, MA
    • ,
  • Huiyun Gao, MD

      Affiliations

    • Division of Cardiovascular Medicine, University Hospitals Case Medical Center, Case Western Reserve University School of Medicine, Cleveland, OH
    • ,
  • Aruna D. Pradhan, MD

      Affiliations

    • Center for Cardiovascular Disease Prevention, Brigham and Women's Hospital, Boston, MA
    • ,
  • Aileen M. Healy, PhD

      Affiliations

    • Division of Cardiovascular Medicine, University Hospitals Case Medical Center, Case Western Reserve University School of Medicine, Cleveland, OH
    • ,
  • Jacki Buros, BS

      Affiliations

    • Thrombolysis in Myocardial Infarction (TIMI) Study Group, Brigham and Women's Hospital, Boston, MA
    • ,
  • Carolyn H. McCabe, BS

      Affiliations

    • Thrombolysis in Myocardial Infarction (TIMI) Study Group, Brigham and Women's Hospital, Boston, MA
    • ,
  • Peter Libby, MD

      Affiliations

    • Cardiovascular Division, Brigham and Women's Hospital, Boston, MA
    • Donald W. Reynolds Center for Clinical Cardiovascular Research, Brigham and Women's Hospital, Women's Hospital, Boston, MA
    • Department of Medicine, Harvard Medical School, Boston, MA
    • ,
  • Christopher P. Cannon, MD

      Affiliations

    • Thrombolysis in Myocardial Infarction (TIMI) Study Group, Brigham and Women's Hospital, Boston, MA
    • Cardiovascular Division, Brigham and Women's Hospital, Boston, MA
    • Department of Medicine, Harvard Medical School, Boston, MA
    • ,
  • Eugene Braunwald, MD

      Affiliations

    • Thrombolysis in Myocardial Infarction (TIMI) Study Group, Brigham and Women's Hospital, Boston, MA
    • Cardiovascular Division, Brigham and Women's Hospital, Boston, MA
    • Department of Medicine, Harvard Medical School, Boston, MA
    • ,
  • Daniel I. Simon, MD

      Affiliations

    • Division of Cardiovascular Medicine, University Hospitals Case Medical Center, Case Western Reserve University School of Medicine, Cleveland, OH
    • Corresponding Author InformationReprint requests: David A. Morrow, MD, MPH, is to be contacted at TIMI Study Group/Cardiovascular Division, Brigham and Women's Hospital, 75 Francis Street, Boston, MA 02115. Daniel I. Simon, MD, Division of Cardiovascular Medicine, University Hospitals Case Medical Center, 11100 Euclid Avenue Lakeside 3001, Cleveland, OH 44106.

Received 29 April 2007; accepted 20 August 2007. published online 12 October 2007.

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 The PROVE IT-TIMI 22 trial was supported by Bristol-Myers Squibb, Princeton, NJ. Drs Morrow and Sabatine are supported in part by National Institutes of Health grant U01 HL083-1341. This work was also supported in part by grants from the National Institutes of Health (HL57506 and HL60942 to Dr Simon). Dr Pradhan is supported by funding from the National Institutes of Health (HL082740). Dr Libby is supported by research funds from the Leducq Foundation (Paris, France), the Doris Duke Foundation (New York, NY), and the Donald W. Reynolds Foundation (Las Vegas, NV).

PII: S0002-8703(07)00704-1

doi:10.1016/j.ahj.2007.08.018

American Heart Journal
Volume 155, Issue 1 , Pages 49-55, January 2008

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