American Heart Journal
Volume 153, Issue 1 , Pages 66.e9-66.e16 , January 2007

A comparison of prasugrel and clopidogrel loading doses on platelet function: magnitude of platelet inhibition is related to active metabolite formation

  • John T. Brandt, MD

      Affiliations

    • Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, IN
    • Corresponding Author InformationReprint requests: John T. Brandt, MD, Lilly Research Laboratories, Eli Lilly and Company, Lilly Corporate Center DC 2133, Indianapolis, IN 46285.
    • ,
  • Christopher D. Payne, MS

      Affiliations

    • Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, IN
    • ,
  • Stephen D. Wiviott, MD

      Affiliations

    • TIMI Study Group, Cardiovascular Division, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA
    • ,
  • Govinda Weerakkody, PhD

      Affiliations

    • Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, IN
    • ,
  • Nagy A. Farid, PhD

      Affiliations

    • Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, IN
    • ,
  • David S. Small, PhD

      Affiliations

    • Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, IN
    • ,
  • Joseph A. Jakubowski, PhD

      Affiliations

    • Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, IN
    • ,
  • Hideo Naganuma, PhD

      Affiliations

    • Sankyo Co, Ltd, Tokyo, Japan
    • ,
  • Kenneth J. Winters, MD

      Affiliations

    • Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, IN

Received 20 April 2006 ,Accepted 9 October 2006.

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 This study was funded by Eli Lilly and Company and Sankyo Co, Ltd., Tokyo, Japan.

PII: S0002-8703(06)00902-1

doi: 10.1016/j.ahj.2006.10.010

American Heart Journal
Volume 153, Issue 1 , Pages 66.e9-66.e16 , January 2007

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