American Heart Journal
Volume 152, Issue 4 , Pages 627-635, October 2006

Evaluation of prasugrel compared with clopidogrel in patients with acute coronary syndromes: design and rationale for the TRial to assess Improvement in Therapeutic Outcomes by optimizing platelet InhibitioN with prasugrel Thrombolysis In Myocardial Infarction 38 (TRITON-TIMI 38)

  • Stephen D. Wiviott, MD

      Affiliations

    • TIMI Study Group, Cardiovascular Division, Department of Medicine, Brigham and Women's Hospital, Boston, MA
    • Corresponding Author InformationReprint requests: Stephen D. Wiviott, MD, TIMI Study Group, Cardiovascular Division, Brigham and Women's Hospital, 75 Francis Street, Boston, MA 02115.
  • ,
  • Elliott M. Antman, MD

      Affiliations

    • TIMI Study Group, Cardiovascular Division, Department of Medicine, Brigham and Women's Hospital, Boston, MA
  • ,
  • C. Michael Gibson, MD

      Affiliations

    • TIMI Study Group, Cardiovascular Division, Department of Medicine, Brigham and Women's Hospital, Boston, MA
  • ,
  • Gilles Montalescot, MD

      Affiliations

    • Groupe Hospitalier Pitie-Salpetriere, Paris, France
  • ,
  • Jeffrey Riesmeyer, MD

      Affiliations

    • Eli Lilly and Company, Indianapolis, IN
  • ,
  • Govinda Weerakkody, PhD

      Affiliations

    • Eli Lilly and Company, Indianapolis, IN
  • ,
  • Kenneth J. Winters, MD

      Affiliations

    • Eli Lilly and Company, Indianapolis, IN
  • ,
  • Jeffrey W. Warmke, PhD

      Affiliations

    • Sankyo Pharma Inc, Parsippany, NJ
  • ,
  • Carolyn H. McCabe, BS

      Affiliations

    • TIMI Study Group, Cardiovascular Division, Department of Medicine, Brigham and Women's Hospital, Boston, MA
  • ,
  • Eugene Braunwald, MD

      Affiliations

    • TIMI Study Group, Cardiovascular Division, Department of Medicine, Brigham and Women's Hospital, Boston, MA
  • ,
  • for the TRITON-TIMI 38 Investigators

Received 23 December 2005; accepted 13 April 2006. published online 04 July 2006.

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 The TRITON-TIMI 38 trial is supported by Eli Lilly and Company, Indianapolis, IN, and Daiichi Sankyo Co., Parsippany, NJ.

PII: S0002-8703(06)00348-6

doi:10.1016/j.ahj.2006.04.012

American Heart Journal
Volume 152, Issue 4 , Pages 627-635, October 2006