American Heart Journal
Volume 151, Issue 5 , Pages 976.e7-976.e11 , May 2006

Lack of effect of enteric coating on aspirin-induced inhibition of platelet aggregation in healthy volunteers

Received 18 August 2005 ,Accepted 5 February 2006.

  • Image Result

    Regression plot for all data points for the point-of-care platelet assay (ARU) on the y-axis and optical aggregometry with AA (maximal inhibition, % aggregation) on the x-axis. The two clusters corres

    Regression plot for all data points for the point-of-care platelet assay (ARU) on the y-axis and optical aggregometry with AA (maximal inhibition, % aggregation) on the x-axis. The two clusters correspond to values before and after aspirin treatment.

  • Image Result
    Enteric-coated and standard aspirin effect on platelet inhibition as measured by the point-of-care platelet assay. Open circles indicate individual subjects. Adjacent to them are the mean and SD value

    Enteric-coated and standard aspirin effect on platelet inhibition as measured by the point-of-care platelet assay. Open circles indicate individual subjects. Adjacent to them are the mean and SD values. BL, Baseline; STD, standard.

  • Image Result
    Enteric-coated and standard aspirin effect on platelet inhibition as measured by optical aggregometry. Open circles indicate individual subjects. Adjacent to them are the mean and SD values.

    Enteric-coated and standard aspirin effect on platelet inhibition as measured by optical aggregometry. Open circles indicate individual subjects. Adjacent to them are the mean and SD values.

 This study was funded by the Cleveland Clinic Foundation Research Programs Council and the Department of Cardiovascular Medicine. The VerifyNow assays were donated without charge by Accumetrics, Inc, San Diego, CA.

PII: S0002-8703(06)00140-2

doi: 10.1016/j.ahj.2006.02.017

American Heart Journal
Volume 151, Issue 5 , Pages 976.e7-976.e11 , May 2006