American Heart Journal
Volume 152, Issue 3 , Pages 442-447 , September 2006

ASymptomatic atrial fibrillation and Stroke Evaluation in pacemaker patients and the atrial fibrillation Reduction atrial pacing Trial (ASSERT)

  • Stefan H. Hohnloser, MD

      Affiliations

    • Division of Electrophysiology, Department of Cardiology, J.W. Goethe-University, Frankfurt, Germany
    • Corresponding Author InformationReprint requests: Stefan H. Hohnloser MD, Division of Electrophysiology, Department of Cardiology, J.W. Goethe-University, Frankfurt, Germany.
    • ,
  • Alessandro Capucci, MD

      Affiliations

    • Cardiology Department, Hospital Civile, Piacenza, Italy
    • ,
  • Eric Fain, MD

      Affiliations

    • Caridac Rythm Management Division, St. Jude Medical, Sylmar, CA
    • ,
  • Michael R. Gold, MD

      Affiliations

    • Division of Cardiology, Medical University of South Carolina, SC
    • ,
  • Isabelle C. van Gelder, MD

      Affiliations

    • Department of Cardiology, Thoraxcenter, University of Groningen, Groningen, The Netherlands
    • ,
  • Jeff Healey, MD

      Affiliations

    • Department of Medicine, McMaster University, Hamilton, Ontario, Canada
    • ,
  • Carsten W. Israel, MD

      Affiliations

    • Division of Electrophysiology, Department of Cardiology, J.W. Goethe-University, Frankfurt, Germany
    • ,
  • Chu P. Lau, MD

      Affiliations

    • Cardiology Division, Department of Medicine, University of Hong Kong, Hong Kong, China
    • ,
  • Carlos Morillo, MD

      Affiliations

    • Department of Medicine, McMaster University, Hamilton, Ontario, Canada
    • ,
  • Stuart J. Connolly, MD

      Affiliations

    • Department of Medicine, McMaster University, Hamilton, Ontario, Canada
    • ,
  • on behalf of the ASSERT Investigators and Committees

Received 29 November 2005 ,Accepted 5 February 2006.

References 

  1. Psaty BM, Manolio TA, Kuller LH, et al. Incidence of and risk factors for atrial fibrillation in older adults. Circulation. 1997;96:2455–2461
  2. Wolf PA, Kannel WB, McGee DL, et al. Duration of atrial fibrillation and imminence of stroke: the Framingham Study. Stroke. 1983;14:664–667
  3. Lin H-J, Wolf PM, Benjamin EJ, et al. Newly diagnosed atrial fibrillation and acute stroke: the Framingham Study. Stroke. 1995;26:1527–1530
  4. Page RL, Wilkinson WE, Clair WK, et al. Asymptomatic arrhythmias in patients with symptomatic paroxysmal atrial fibrillation and paroxysmal supraventricular tachycardia. Circulation. 1994;89:224–227
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  9. Carlson MD, Ip J, Messendger J, et al. A new pacemaker algorithm for the treatment of atrial fibrillation. J Am Coll Cardiol. 2003;42:627–633
  10. Padeletti L, Pürefellner H, Adler SW, et al. Combined efficacy of atrial septal lead placement and atrial pacing algorithms for prevention of paroxysmal atrial tachyarrhythmia. J Cardiovasc Electrophysiol. 2003;14:1189–1195
  11. Lee MA, Weachter R, Pollak S, et al. The effect of atrial pacing therapies on atrial tachyarrhythmia burden and frequency. J Am Coll Cardiol. 2003;41:1926–1932
  12. Kerr CR, Connolly SJ, Abdollah H, et al. Canadian Trial of Physiological Pacing: effects of physiological pacing during long-term follow-up. Circulation. 2004;109:357–362
  13. Morillo CA, Klein GJ, Jones DL, et al. Chronic rapid atrial pacing. Structural, functional and electrophysiological characteristics of a new model of sustained atrial fibrillation. Circulation. 1995;91:1588–1595
  14. Wijffels MC, Kirchhof CJ, Dorland R, et al. Atrial fibrillation begets atrial fibrillation. A study in awake chronically instrumented goats. Circulation. 1995;92:1954–1968
  15. Li D, Fareh S, Leung TK, et al. Promotion of atrial fibrillation by heart failure in dogs: atrial remodeling of a different sort. Circulation. 1999;100:87–95
  16. Pollack WM, Simmons JD, Interian A, et al. Clinical utility of intraatrial pacemaker stored electrograms to diagnose atrial fibrillation and flutter. Pacing Clin Electrophysiol. 2001;24:424–429
  17. Gillis AM, Morck M. Atrial fibrillation after DDDR pacemaker implantation. J Cardiovasc Electrophysiol. 2002;13:542–547
  18. Defaye P, Dournaux F, Mouton E. Prevalence of supraventricular arrhythmias from the automated analysis of data stored in the DDD pacemakers of 617 patients: the AIDA study. The AIDA Multicenter Study Group. Automatic Interpretation for Diagnosis Assistance. Pacing Clin Electrophysiol. 1998;21:250–255
  19. Israel CW, Grönefeld G, Ehrlich JR, et al. Long-term risk of recurrent atrial fibrillation as documented by an implantable monitoring device. Implications for optimal patient care. J Am Coll Cardiol. 2004;43:47–52
  20. Savelieva I, Camm AJ. Clinical relevance of silent atrial fibrillation: prevalence, prognosis, quality of life, and management. J Interv Card Electrophysiol. 2000;4:369–382

PII: S0002-8703(06)00139-6

doi: 10.1016/j.ahj.2006.02.016

American Heart Journal
Volume 152, Issue 3 , Pages 442-447 , September 2006

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