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American Heart Journal
Volume 151, Issue 6
, Pages 1131-1138
, June 2006
Argatroban: Update
References
- Novastan (brand of argatroban): a small molecule, direct thrombin inhibitor. Semin Thromb Hemost. 1997;23:503–516
- Effects of the synthetic thrombin inhibitor argatroban on fibrin- or clot-incorporated thrombin: comparison with heparin and recombinant hirudin. Thromb Haemost. 1994;72:381–386
- Inhibition by Argatroban, a specific thrombin inhibitor, of platelet activation by fibrin clot-associated thrombin. Thromb Haemost. 1996;75:154–160
- . The pharmacokinetics and pharmacodynamics of argatroban: effects of age, gender, and hepatic or renal dysfunction. Pharmacotherapy. 2000;20:318–329
- Assessment of the potential pharmacokinetic and pharmacodynamic interactions between erythromycin and argatroban. J Clin Pharmacol. 1999;39:513–519
- Comparison of anticoagulation effects and safety of argatroban and heparin in healthy subjects. Pharmacotherapy. 2000;20:756–770
- Evidence for a rebound coagulation phenomenon after cessation of a 4-hour infusion of a specific thrombin inhibitor in patients with unstable angina pectoris. J Am Coll Cardiol. 1993;21:1039–1047
- In vivo thrombin inhibition enhances and sustains arterial recanalization with recombinant tissue-type plasminogen activator. Circ Res. 1990;67:1552–1561
- Prevention of platelet-rich arterial thrombosis by selective thrombin inhibition. Circulation. 1989;81:219–225
- Persistent inhibition of arterial thrombosis by a 1-hour intravenous infusion of argatroban, a selective thrombin inhibitor. Coron Artery Dis. 1992;3:407–414
- Comparative effects of aspirin, a synthetic thrombin inhibitor and a monoclonal antiplatelet glycoprotein IIb/IIIa antibody on coronary artery reperfusion, reocclusion, and bleeding with recombinant tissue-type plasminogen activator in a canine preparation. J Am Coll Cardiol. 1990;16:714–722
- Effects of argatroban and heparin on thrombus formation and tissue plasminogen activator-induced thrombolysis in a microvascular thrombosis model. Thromb Res. 2003;109:55–64
- Extension of the therapeutic window for recombinant tissue plasminogen activator with argatroban in a rat model of embolic stroke. Stroke. 2001;32:2635–2640
- A multi-center, randomized study of argatroban versus heparin as adjunct to tissue plasminogen activator (tPA) in acute myocardial infarction: myocardial infarction with novastan and tPA (MINT) study. J Am Coll Cardiol. 1999;33:1880–1885
- Argatroban and alteplase in patients with acute myocardial infarction: the ARGAMI Study. J Thromb Thrombolysis. 2000;10:233–240
- . Argatroban versus heparin as adjuvant therapy to thrombolysis for acute myocardial infarction: safety considerations—ARGAMI-2 Study. Circulation. 1998;98(Suppl 17):I453–I454
- . Results from late breaking clinical trials session at ACC'97. J Am Coll Cardiol. 1997;30:1–7
- Argatroban anticoagulation during percutaneous coronary intervention in patients with heparin-induced thrombocytopenia. Catheter Cardiovasc Interv. 2002;57:177–184
- Argatroban anticoagulation in conjunction with glycoprotein IIb/IIIa inhibition in patients undergoing percutaneous coronary intervention: an open-label, non-randomized pilot study. J Thromb Thrombolysis. 2004;18:31–37
- Pharmacokinetics and pharmacodynamics of argatroban in combination with a platelet glycoprotein IIB/IIIA receptor antagonist in patients undergoing percutaneous coronary intervention. J Clin Pharmacol. 2004;44:981–990
- Clinical experience of argatroban for anticoagulation in cardiovascular surgery. Jpn J Thorac Cardiovasc Surg. 2000;48:39–46
- . Argatroban as an alternative anticoagulant for patients with heparin allergy during coronary bypass surgery. Heart Vessels. 2003;18:40–42
- Failure of argatroban anticoagulation during off-pump coronary artery bypass surgery. Ann Thorac Surg. 2004;77:711–713
- . Heparin-induced thrombocytopenia: a ten-year retrospective. Annu Rev Med. 1999;50:129–147
- . A 14-year study of heparin-induced thrombocytopenia. Am J Med. 1996;101:502–507
- Failure of early heparin cessation as treatment for heparin-induced thrombocytopenia. Am J Med. 1999;106:629–635
- Laboratory diagnosis of heparin-induced thrombocytopenia. Clin Appl Thromb Hemost. 1999;(5 Suppl 1):S21–S27
- Argatroban anticoagulation in patients with heparin-induced thrombocytopenia. Arch Intern Med. 2003;163:1849–1856
- Argatroban anticoagulant therapy in patients with heparin-induced thrombocytopenia. Circulation. 2001;103:1838–1843
- . Stroke in patients with heparin-induced thrombocytopenia and the effect of argatroban therapy. Crit Care Med. 2004;32:976–980
- Argatroban anticoagulation in patients with a history of heparin-induced thrombocytopenia. Thromb Res. 2005;116:121–126
- . Temporal aspects of heparin-induced thrombocytopenia. N Engl J Med. 2001;344:1286–1292
- . Clinical significance of a borderline titer in a negative ELISA test for heparin-induced thrombocytopenia. Am J Clin Pathol. 2003;119:61–65
- . Effect of the thrombin inhibitor argatroban in acute cerebral thrombosis. Semin Thromb Hemost. 1997;23:531–534
- Argatroban anticoagulation in patients with acute ischemic stroke. Stroke. 2004;35:1677–1682
- Tpa ARgatroban sTroke Study (TARTS). Stroke. 2005;36:447
- Platelet count, anti-heparin/platelet factor 4 antibodies and tissue factor pathway inhibitor plasma antigen level in chronic dialysis. Thromb Res. 1998;89:115–122
- A prospective comparison of three argatroban treatment regimens during hemodialysis in end-stage renal disease. Kidney Int. 2004;66:2446–2453
- Argatroban and renal replacement therapy in patients with heparin-induced thrombocytopenia. Ann Pharmacother. 2005;39:231–236
- Argatroban manufacturer's website. http://www.argatroban.com (15 March 2005).
- Argatroban dosing in intensive care patients with acute renal failure and liver dysfunction. Pharmacotherapy. 2004;24:409–414
- Excessive argatroban anticoagulation for heparin-induced thrombocytopenia. Ann Pharmacother. 2003;37:652–654
- Interpreting the international normalized ratio (INR) in individuals receiving argatroban and warfarin. Thromb Haemost. 2001;85:435–440
- Transition from argatroban to oral anticoagulation with phenprocoumon or acenocoumarol: effects on prothrombin time, activated partial thromboplastin time, and Ecarin Clotting Time. Thromb Haemost. 2004;91:1137–1145
- Recombinant factor VIIa reverses the anticoagulant effects of argatroban, bivalirudin, fondaparinux, enoxaparin, and heparin as assessed ex vivo by thromboelastography. Blood. 2004;104:Abstract
- Argatroban as anticoagulant in cardiopulmonary bypass in an infant and attempted reversal with recombinant activated factor VII. Anesthesiology. 2004;100:443–445
Dr Jang has received research grant and/or consultancy fees from Boston Scientific Corp, Guidant, GlaxoSmithKline, and Mitsubishi-Pharma.
PII: S0002-8703(05)00846-X
doi: 10.1016/j.ahj.2005.09.002
© 2006 Mosby, Inc. All rights reserved.
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American Heart Journal
Volume 151, Issue 6
, Pages 1131-1138
, June 2006
