Design and rationale of the Clinical Outcomes Utilizing Revascularization and Aggressive DruG Evaluation (COURAGE) trial: Veterans Affairs Cooperative Studies Program no. 424

Boden, William E.; O'Rourke, Robert A.; Teo, Koon K.; Hartigan, Pamela M.; Maron, David J.; Kostuk, William; Knudtson, Merril; Dada, Marcin; Casperson, Paul; Harris, Crystal L.; Spertus, John A.; Shaw, Leslee; Chaitman, Bernard R.; Mancini, G.B. John; Berman, Daniel S.; Weintraub, William S.; On behalf of the COURAGE trial coprincipal investigators and study coordinators,

doi:10.1016/j.ahj.2005.08.015

« Previous Next »American Heart Journal
Volume 151, Issue 6 , Pages 1173-1179, June 2006

Design and rationale of the Clinical Outcomes Utilizing Revascularization and Aggressive DruG Evaluation (COURAGE) trial:

Veterans Affairs Cooperative Studies Program no. 424

William E. Boden, MD
- VA Connecticut Healthcare System, West Haven, CT
- Hartford Hospital and the University of Connecticut School of Medicine, Hartford, CT
- Reprint requests: William E. Boden, MD, Division of Cardiology, Hartford Hospital, 80 Seymour Street, Hartford, CT 06102-5037.
Robert A. O'Rourke, MD
- South Texas Veterans Healthcare System and University of Texas Health Science Center at San Antonio, San Antonio, TX
Koon K. Teo, MB, BCh, PhD
- McMaster University Health Sciences Centre, Hamilton, Ontario, Canada
Pamela M. Hartigan, PhD
- Veterans Affairs Cooperative Studies Program Coordinating Center, VA Connecticut Healthcare System, West Haven, CT
David J. Maron, MD
- Vanderbilt University Medical Center, Nashville, TN
William Kostuk, MD
- London Health Science Center, London, Ontario, Canada
Merril Knudtson, MD
- Foothills Hospital, Calgary, Alberta, Canada
Marcin Dada, MD
- VA Connecticut Healthcare System, West Haven, CT
- Hartford Hospital and the University of Connecticut School of Medicine, Hartford, CT
Paul Casperson, PhD
- South Texas Veterans Healthcare System and University of Texas Health Science Center at San Antonio, San Antonio, TX
Crystal L. Harris, PharmD
- Veteran Affairs Cooperative Studies Program Clinical Research Pharmacy Coordinating Center, Albuquerque, NM
John A. Spertus, MD, MPH
- Mid-America Heart Institute, Kansas City, MO
Leslee Shaw, PhD
- Cedars-Sinai Medical Center, Los Angeles, CA
Bernard R. Chaitman, MD
- Saint Louis University School of Medicine, St Louis, MO
G.B. John Mancini, MD
- Vancouver Hospital and Health Science Centre, Vancouver, British Columbia, Canada
Daniel S. Berman, MD
- Cedars-Sinai Medical Center, Los Angeles, CA
William S. Weintraub, MD
- Emory Center for Outcomes Research, Emory University, Newark, DE
On behalf of the COURAGE trial coprincipal investigators and study coordinators

Received 24 May 2005; accepted 27 August 2005.

This study was supported by the Cooperative Studies Program of the Department of Veterans Affairs Office of Research and Development, in collaboration with the Canadian Institutes of Health Research. Unrestricted research grants have been obtained from Merck & Co; Pfizer Pharmaceuticals; Bristol-Myers Squibb Medical Imaging; Fujisawa; Kos Pharmaceuticals; Data Scope; Astra Zeneca Pharmaceuticals; Astra Zeneca–Canada; Schering-Plough Corporation, Ltd; Sanofi-Aventis, Inc; First Horizon; and GE Healthcare. All industrial funding in support of the trial has been directed through the Department of Veterans Affairs.