American Heart Journal
Volume 151, Issue 5 , Pages 969-975 , May 2006

Missed opportunities in the secondary prevention of myocardial infarction: An assessment of the effects of statin underprescribing on mortality

  • Peter C. Austin, PhD

      Affiliations

    • Institute for Clinical Evaluative Sciences, Toronto, Ontario, Canada
    • Department of Public Health Sciences, University of Toronto, Toronto, Ontario, Canada
    • Department of Health Policy, Management and Evaluation, University of Toronto, Toronto, Ontario, Canada
    • Corresponding Author InformationReprint requests: Peter C. Austin, PhD, Institute for Clinical Evaluative Sciences, G1 06, 2075 Bayview Avenue, Toronto, Ontario, Canada M4N 3M5.
  • ,
  • Muhammad M. Mamdani, PharmD, MA, MPH

      Affiliations

    • Institute for Clinical Evaluative Sciences, Toronto, Ontario, Canada
    • Department of Health Policy, Management and Evaluation, University of Toronto, Toronto, Ontario, Canada
    • Faculty of Pharmacy, University of Toronto, Toronto, Ontario, Canada
  • ,
  • David N. Juurlink, MD, PhD

      Affiliations

    • Institute for Clinical Evaluative Sciences, Toronto, Ontario, Canada
    • Department of Health Policy, Management and Evaluation, University of Toronto, Toronto, Ontario, Canada
    • Clinical Epidemiology and Health Care Research Program (Sunnybrook and Women's College Site), University of Toronto, Toronto, Canada
    • Division of General Internal Medicine, Sunnybrook and Women's College Health, Sciences Centre and the University of Toronto, Toronto, Ontario, Canada
  • ,
  • David A. Alter, MD, PhD

      Affiliations

    • Institute for Clinical Evaluative Sciences, Toronto, Ontario, Canada
    • Department of Health Policy, Management and Evaluation, University of Toronto, Toronto, Ontario, Canada
    • Division of Cardiology, Sunnybrook and Women's College Health Sciences Centre, Toronto, Ontario, Canada
  • ,
  • Jack V. Tu, MD, PhD

      Affiliations

    • Institute for Clinical Evaluative Sciences, Toronto, Ontario, Canada
    • Department of Public Health Sciences, University of Toronto, Toronto, Ontario, Canada
    • Department of Health Policy, Management and Evaluation, University of Toronto, Toronto, Ontario, Canada
    • Clinical Epidemiology and Health Care Research Program (Sunnybrook and Women's College Site), University of Toronto, Toronto, Canada
    • Division of General Internal Medicine, Sunnybrook and Women's College Health, Sciences Centre and the University of Toronto, Toronto, Ontario, Canada

Received 18 March 2005 ,Accepted 17 June 2005.

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 The Institute for Clinical Evaluative Sciences is supported in part by a grant from the Ontario Ministry of Health and Long-term Care. The opinions, results, and conclusions are those of the authors and no endorsement by the Ministry of Health and Long-term Care or by the Institute for Clinical Evaluative Sciences is intended or should be inferred. This research was supported in part by operating grants from the Canadian Institutes of Health Research (CIHR) and the Heart and Stroke Foundation to the Canadian Cardiovascular Outcomes Research Team. Drs Austin, Mamdani, and Juurlink are supported by New Investigator awards from the CIHR. Dr Juurlink is also supported by the University of Toronto Drug Safety Research Group. Dr Alter is supported by a New Investigator award from the CIHR and the Heart and Stroke Foundation. Dr Tu is supported by a Canada Research Chair in Health Services Research.

PII: S0002-8703(05)00651-4

doi: 10.1016/j.ahj.2005.06.034

American Heart Journal
Volume 151, Issue 5 , Pages 969-975 , May 2006