American Heart Journal
Volume 151, Issue 4 , Pages 923-927 , April 2006

Impairment of physical exercise capacity in healthy postmenopausal women

  • Giuseppe Mercuro, MD

      Affiliations

    • Department of Cardiovascular and Neurological Sciences, University of Cagliari, Cagliari, Sardinia, Italy
    • Corresponding Author InformationReprint requests: Prof Giuseppe Mercuro, Dipartimento di Scienze Cardiovascolari e Neurologiche, Policlinico Universitario, S.S 554, bivio Sestu, 09042, Monserrato, Sardinia, Italy.
    • ,
  • Francesca Saiu, MD

      Affiliations

    • Department of Cardiovascular and Neurological Sciences, University of Cagliari, Cagliari, Sardinia, Italy
    • ,
  • Martino Deidda

      Affiliations

    • Department of Cardiovascular and Neurological Sciences, University of Cagliari, Cagliari, Sardinia, Italy
    • ,
  • Silvia Mercuro

      Affiliations

    • Department of Cardiovascular and Neurological Sciences, University of Cagliari, Cagliari, Sardinia, Italy
    • ,
  • Cristiana Vitale, MD

      Affiliations

    • Cardiovascular Research Unit—San Raffaele–H—Rome Italy
    • ,
  • Giuseppe M.C. Rosano, MD, PhD

      Affiliations

    • Cardiovascular Research Unit—San Raffaele–H—Rome Italy

Received 14 April 2005 ,Accepted 17 June 2005.

References 

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  2. Mercuro G, Zoncu S, Cerchi A, et al. Can menopause be considered an independent risk factor for cardiovascular disease?. Ital Heart J. 2001;2:719–727
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  5. Moncada S, Higgs A. The l-arginine–nitric oxide pathway. N Engl J Med. 1993;329:2002–2012
  6. Mercuro G, Longu G, Zoncu S, et al. Impaired forearm blood flow and vasodilator reserve in healthy postmenopausal women. Am Heart J. 1999;137:692–697
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  11. Herrington DM, Braden GA, Williams JK, et al. Endothelium-dependent coronary vasomotor responsiveness in postmenopausal women with and without estrogen therapy. Am J Cardiol. 1994;73:951–952
  12. Saab PG, Matthews KA, Stoney CM, et al. Premenopausal and postmenopausal women differ in their cardiovascular and neuroendocrine responses to behavioral stressors. Psychophysiology. 1989;26:270–280
  13. Owens JF, Stoney CM, Matthews KA. Menopausal status influences ambulatory blood pressure levels and blood pressure changes during mental stress. Circulation. 1993;88:2794–2802
  14. Mercuro G, Podda A, Pitzalis L, et al. Evidence of a role of endogenous estrogen in the modulation of autonomic nervous system. Am J Cardiol. 2000;85:787–789
  15. Yoshioka J, Node K, Hasegawa S, et al. Impaired cardiac response to exercise in postmenopausal women: relationship with peripheral vascular function. Nucl Med Commun. 2003;24:383–389
  16. Redberg RF, Nishino M, McElhinney DB, et al. Long-term estrogen replacement therapy is associated with improved exercise capacity in postmenopausal women without known coronary artery disease. Am Heart J. 2000;139:739–744
  17. Ozdemir K, Celik C, Altunkeser BB, et al. Effect of postmenopausal hormone replacement therapy on cardiovascular performance. Maturitas. 2004;47:107–113
  18. Kirwan LD, MacLusky NJ, Shapiro HM, et al. Acute and chronic effects of hormone replacement therapy on the cardiovascular system in healthy postmenopausal women. J Clin Endocrinol Metab. 2004;89:1618–1629
  19. Uusi-Rasi K, Beck TJ, Sievanen H, et al. Associations of hormone replacement therapy with bone structure and physical performance among postmenopausal women. Bone. 2003;32:704–710

PII: S0002-8703(05)00646-0

doi: 10.1016/j.ahj.2005.06.027

American Heart Journal
Volume 151, Issue 4 , Pages 923-927 , April 2006

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