American Heart Journal
Volume 151, Issue 2 , Pages 308-315 , February 2006

External validation of a percutaneous coronary intervention mortality prediction model in patients with acute coronary syndromes

  • Jaroslav Hubacek, MD, MSc

      Affiliations

    • Department of Medicine, University of Calgary, Calgary, Alberta, Canada
    • ,
  • P. Diane Galbraith, BN

      Affiliations

    • Department of Medicine, University of Calgary, Calgary, Alberta, Canada
    • The APPROACH Offices, Calgary and Edmonton, Alberta, Canada
    • ,
  • Min Gao, PhD

      Affiliations

    • The British Columbia Cardiac Registries, Vancouver, British Columbia, Canada
    • ,
  • Karin Humphries, MBA, DSc

      Affiliations

    • The British Columbia Cardiac Registries, Vancouver, British Columbia, Canada
    • Department of Medicine, University of British Columbia, Vancouver, British Columbia, Canada
    • ,
  • Michelle M. Graham, MD, FRCP(C)

      Affiliations

    • Department of Medicine, University of Alberta, Edmonton, Alberta, Canada
    • ,
  • Merril L. Knudtson, MD, FRCP(C)

      Affiliations

    • Department of Medicine, University of Calgary, Calgary, Alberta, Canada
    • ,
  • William A. Ghali, MD, MPH

      Affiliations

    • Department of Medicine, University of Calgary, Calgary, Alberta, Canada
    • Community Health Sciences, University of Calgary, Calgary, Alberta, Canada
    • Corresponding Author InformationReprint requests: Dr Whilliam A Ghali, Faculty of Medicine, University of Calgary, 3330 Hospital Drive NW, Calgary, Alberta, Canada T2N 4N1.
    • ,
  • for APPROACH investigators

Received 4 May 2004 ,Accepted 29 April 2005.

References 

  1. O'Connor GT, Malenka DJ, Quinton H, et al. Multivariate prediction of in-hospital mortality after percutaneous coronary interventions in 1994-1996. J Am Coll Cardiol. 1999;34:681–691
  2. Hannan EL, Racz M, Ryan TJ, et al. Coronary angioplasty volume-outcome relationships for hospitals and cardiologists. JAMA. 1997;279:892–898
  3. Hannan EL, Arani DJ, Johnson LW, et al. Percutaneous transluminal coronary angioplasty in New York State: risk factors and outcomes. JAMA. 1992;268:3092–3097
  4. Shaw RE, Anderson V, Brindis RG, et al. Development of a risk adjustment mortality model using the American College of Cardiology–National Cardiovascular Data Registry (ACC-NCDR) experience: 1998-2000. J Am Coll Cardiol. 2002;39:1101–1112
  5. Ellis SG, Weintraub W, Holmes DR, et al. Relation of operator volume and experience to procedural outcome of percutaneous coronary revascularization at hospitals with high interventional volumes. Circulation. 1997;96:2479–2484
  6. Moscucci M, Kline-Rogers E, Share D, et al. Simple bedside additive tool for prediction of in-hospital mortality after percutaneous coronary interventions. Circulation. 2001;104:263–268
  7. Singh M, Lennon RJ, Holmes DR, et al. Correlates of procedural complications and a simple integer risk score for percutaneous coronary intervention. J Am Coll Cardiol. 2002;40:387–393
  8. Holmes DR, Berger PB, Garratt KN, et al. Application of the New York State PTCA Mortality Model in Patients Undergoing Stent Implantation. Circulation. 2000;102:517–522
  9. Cannon CP, Weintraub WS, Demopoulos LA, et al. Comparison of early invasive and conservative strategies in patients with unstable coronary syndromes treated with the glycoprotein IIb/IIIa inhibitor tirofiban. N Engl J Med. 2001;344:1879–1887
  10. Sheridan PJ, Crossman DC. Critical review of unstable angina and non–ST elevation myocardial infarction. Postgrad Med J. 2002;78:717–726
  11. Braunwald E, Antman EM, Beasley JW, et al. ACC/AHA guideline update for the management of patients with unstable angina and non–ST-segment elevation myocardial infarction—2002: summary article: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Committee on the Management of Patients With Unstable Angina). Circulation. 2002;106:1893–1900
  12. Ghali WA, Knudtson ML on behalf of the APPROACH Investigators. Overview of the Alberta Provincial Project for Outcome Assessment in Coronary Heart Disease. Can J Cardiol. 2000;16:1225–1230
  13. Norris CM, Ghali WA, Knudtson ML, et al. Dealing with missing data in observational health care outcome analyses. J Clin Epidemiol. 2000;53:377–383
  14. Egan JP. Signal detection theory and ROC analysis. New York (NY): Academic Press; 1975;
  15. Ash AA, Shwartz M. Evaluating the performance of risk-adjustment methods: dichotomous measures. In:  Iezzoni LI editors. Risk adjustment for measuring health care outcomes. Ann Arbor (Mich): Health Administration Press; 1994;p. 427–469
  16. Hosmer DW, Lemeshow S. Applied logistic regression. New York (NY): Wiley; 1989;
  17. Ryan TJ, Antman EM, Brooks NH, et al. ACC/AHA guidelines for the management of patients with acute myocardial infarction: executive summary and recommendations. Circulation. 1999;100:1016–1030
  18. Keely EC, Boura JA, Grines CL. Primary angioplasty versus intravenous thrombolytic therapy for acute myocardial infarction: a qualitative review of 23 randomised trials. Lancet. 2003;361:13–20
  19. Boden WE, O'Rourke RA, Crawford MH, et al. Outcomes in patients with acute non–Q-wave myocardial infarction randomly assigned to an invasive as compared with a conservative management strategy (VANQWISH trial). N Engl J Med. 1998;338:1785–1792
  20. Boersma E, Maas ACP, Deckers JW, et al. Early thrombolytic treatment in acute myocardial infarction: reappraisal of the golden hour. Lancet. 1996;348:771–775
  21. Neumann FJ, Kastrati A, Pogatsa-Murray G, et al. Evaluation of prolonged antithrombotic pretreatment (“cooling-off” strategy) before intervention in patients with unstable coronary syndromes. JAMA. 2003;290:1593–1599
  22. Deber RB. Health care reform: lessons from Canada. Am J Public Health. 2003;93:20–24
  23. Brown LD. Comparing health systems in four countries: lessons for the United States. Am J Public Health. 2003;93:52–56
  24. Singh M, Rihal CS, Selzer F, et al. Validation of Mayo Clinic risk adjustment model for in-hospital complications after percutaneous coronary interventions, using the National Heart, Lung, and Blood Institute Dynamic Registry. J Am Coll Cardiol. 2003;42:1722–1728

 Disclosure: There are no associations to disclose that might pose a conflict of interest in connection with submitted manuscript.

 Supported in part by the Institute of Health Economics (WAG, JH), Calgary, Alberta, Canada.

 Dr Knudtson receives partial support from the Libin Trust Fund.

 Dr Ghali is supported by a Government of Canada Research Chair in Health Services Research and by a Health Scholar Award from the Alberta Heritage Foundation for Medical Research, Edmonton, Alberta.

 Ms Galbraith is supported by Canadian Cardiovascular Outcomes Research Team (http://www.ccort.ca) student fellowship, funded by an operating grant from the Canadian Institutes of Health Research and the Heart and Stroke Foundation and TORCH (Tomorrows Research Cardiovascular Health Professionals; http://www.torch.ca) student fellowship.

 Dr Humphries is supported by a Scholar Award from the Michael Smith Foundation, Vancouver, British Columbia, Canada.

 Members of the APPROACH Clinical Steering Committee are Dr William Hui (chair), Dr Stephen Archer, Dr Micheal Curtis, Dr William A Ghali, Dr Michelle Graham, Dr Merril L Knudtson, Dr Arvind Koshal, Dr Andrew Maitland, Dr L Brent Mitchell, and Dr Ross Tsuyuki.

 APPROACH was funded in 1995 by the W Garfield Weston Foundation, with ongoing support from Merck Frosst Canada Inc, Monsanto Canada Inc-Searle, Eli Lilly Canada Inc, Guidant Corporation, Boston Scientific Ltd, Roche Ltd, Johnson & Johnson Inc, CORDIS, and the Province-Wide Services Committee of Alberta Health and Wellness.

 The BC Cardiac Registries have been funded since 1990 by the BC Ministry of Health.

PII: S0002-8703(05)00489-8

doi: 10.1016/j.ahj.2005.04.032

American Heart Journal
Volume 151, Issue 2 , Pages 308-315 , February 2006

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