American Heart Journal
Volume 151, Issue 1 , Pages 158-163 , January 2006

Incidence and predictors of late recurrence after β-radiation therapy with a 188Re-MAG3–filled balloon for diffuse in-stent restenosis

  • Seung-Whan Lee, MD

      Affiliations

    • Department of Medicine, Soonchunhyang University Bucheon Hospital, Bucheon, South Korea
    • ,
  • Seong-Wook Park, MD, PhD

      Affiliations

    • Department of Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, South Korea
    • Corresponding Author InformationReprint requests: Seong-Wook Park, MD, PhD, Department of Medicine, University of Ulsan College of Medicine, Asan Medical Center, 388-1 Poongnap-dong, Songpa-gu, Seoul, 138-736, South Korea.
    • ,
  • Myeong-Ki Hong, MD, PhD

      Affiliations

    • Department of Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, South Korea
    • ,
  • Young-Hak Kim, MD, PhD

      Affiliations

    • Department of Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, South Korea
    • ,
  • Ki Hoon Han, MD

      Affiliations

    • Department of Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, South Korea
    • ,
  • Jun Kim, MD

      Affiliations

    • Department of Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, South Korea
    • ,
  • Jae-Hyeong Park, MD

      Affiliations

    • Department of Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, South Korea
    • ,
  • Sung-Joo Oh, MD

      Affiliations

    • Department of Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, South Korea
    • ,
  • Dae Hyuk Moon, MD, PhD

      Affiliations

    • Department of Nuclear Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, South Korea
    • ,
  • Seung Jun Oh, PhD

      Affiliations

    • Department of Nuclear Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, South Korea
    • ,
  • Cheol Whan Lee, MD, PhD

      Affiliations

    • Department of Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, South Korea
    • ,
  • Jae-Joong Kim, MD, PhD

      Affiliations

    • Department of Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, South Korea
    • ,
  • Seung-Jung Park, MD, PhD

      Affiliations

    • Department of Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, South Korea

Received 28 May 2004 ,Accepted 14 February 2005.

References 

  1. Teirstein PS, Massullo V, Jani S, et al. Catheter-based radiotherapy to inhibit restenosis after coronary stenting. N Engl J Med. 1997;336:1697–1703
  2. Waksman R, Bhargava B, White L, et al. Intracoronary β-radiation therapy inhibits recurrence of in-stent restenosis. Circulation. 2000;101:1895–1898
  3. Waksman R, White RL, Chan RC, et al. Intracoronary γ-radiation therapy after angioplasty inhibits recurrence in patients with in-stent restenosis. Circulation. 2000;101:2165–2171
  4. Park SW, Hong MK, Moon DH, et al. Treatment of diffuse in-stent restenosis with rotational atherectomy followed by radiation therapy with a rhenium-188-mercaptoacetyltriglycine–filled balloon. J Am Coll Cardiol. 2001;38:631–637
  5. Teirstein PS, Massullo V, Jani S, et al. Three-year clinical and angiographic follow-up after intracoronary radiation: results of a randomized clinical trial. Circulation. 2000;101:360–365
  6. Grise MA, Massullo V, Jani S, et al. Five-year clinical follow-up after intracoronary radiation: results of a randomized clinical trial. Circulation. 2002;105:2737–2740
  7. Waksman R, Ajani AE, White RL, et al. Two-year follow-up after beta and gamma intracoronary radiation therapy for patients with diffuse in-stent restenosis. Am J Cardiol. 2001;88:425–428
  8. Meerkin D, Joyal M, Tardif JC, et al. Two-year angiographic follow-up of intracoronary Sr90 therapy for restenosis prevention after balloon angioplasty. Circulation. 2002;106:539–543
  9. Waksman R, Ajani AE, White RL, et al. Five-year follow-up after intracoronary gamma radiation therapy for in-stent restenosis. Circulation. 2004;109:340–344
  10. Brenner DJ, Miller RC, Hall EJ. The radiobiology of intravascular irradiation. Int J Radiat Oncol Biol Phys. 1996;36:805–810
  11. Ajani AE, Waksman R, Cha DH, et al. The impact of lesion length and reference vessel diameter on angiographic restenosis and target vessel revascularization in treating in-stent restenosis with radiation. J Am Coll Cardiol. 2002;39:1290–1296
  12. Brenner DJ, Miller RC. Long-term efficacy of intracoronary irradiation in inhibiting in-stent restenosis. Circulation. 2001;103:1330–1332
  13. Leon MB, Teirstein PS, Moses JW, et al. Localized intracoronary gamma-radiation therapy to inhibit the recurrence of restenosis after stenting. N Engl J Med. 2001;344:250–256
  14. Waksman R, Ajani AE, White RL, et al. Prolonged antiplatelet therapy to prevent late thrombosis after intracoronary gamma-radiation in patients with in-stent restenosis: Washington Radiation for In-Stent Restenosis Trial plus 6 months of clopidogrel (WRIST PLUS). Circulation. 2001;103:2332–2335

 This work was supported by grant no. 1999-2-206-001-3 from the Interdisciplinary Research Program of the KOSEF and the Cardiovascular Research Foundation, Seoul, South Korea.

PII: S0002-8703(05)00161-4

doi: 10.1016/j.ahj.2005.02.011

American Heart Journal
Volume 151, Issue 1 , Pages 158-163 , January 2006

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