American Heart Journal
Volume 149, Issue 5 , Pages 813-819 , May 2005

Impact of invasive management versus noninvasive management on functional status and quality of life following non–Q-wave myocardial infarction: A randomized clinical trial

  • Mark J. Eisenberg, MD, MPH

      Affiliations

    • Jewish General Hospital, Montreal, Quebec, Canada
    • Corresponding Author InformationReprint requests: Mark J. Eisenberg, MD, MPH, Associate Professor of Medicine, Divisions of Cardiology and Clinical Epidemiology, Jewish General Hospital/McGill University, 3755 Cote Ste Catherine Rd/Suite A-118, Montreal, Quebec, Canada H3T 1E2.
    • Doctor Eisenberg is a physician-scientist of the Quebec Foundation for Health Research.
    • ,
  • Flora F. Teng, BSc

      Affiliations

    • Jewish General Hospital, Montreal, Quebec, Canada
    • ,
  • Muhammad R. Chaudhry, MD

      Affiliations

    • Shaikh Zayed Hospital, Lahore, Pakistan
    • ,
  • Jose Ortiz, MD

      Affiliations

    • Louis Stokes Cleveland Veterans Affairs Medical Center, Cleveland, Ohio
    • ,
  • Wojciech Sobkowski, MD

      Affiliations

    • Welland County General Hospital, Welland, Ontario, Canada
    • ,
  • Iftikhar Ebrahim, MD

      Affiliations

    • Pretoria Academic Hospital, Pretoria, South Africa
    • ,
  • Ramesh S. Saligrama, MD

      Affiliations

    • Bhagwan Mahaveer Jain Heart Center, Bangalore, India
    • ,
  • Kerala Serio, MD

      Affiliations

    • University Medical Center, Fresno, Calif
    • ,
  • Ellis Lader, MD

      Affiliations

    • Mid-Valley Cardiology, Kingston, NY
    • ,
  • Louise Pilote, MD, MPH, PhD

      Affiliations

    • Montreal General Hospital, Montreal, Quebec, Canada
    • Doctor Pilote is a physician-scientist of the Canadian Institutes of Health Research.
    • ,
  • for the NQWMI Investigators

Received 2 June 2004 ,Accepted 10 August 2004.

References 

  1. Braunwald E, Antman EM, Beasley JW, et al. ACC/AHA 2002 guideline update for the management of patients with unstable angina and non–ST-segment elevation myocardial infarction—summary article: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Committee on the Management of Patients with Unstable Angina). J. Am. Coll. Cardiol. 2002;1366–1374
  2. Fragmin and Fast Revascularization During Instability in Coronary Artery Disease (FRISC II) Investigators. Invasive compared with noninvasive treatment in unstable coronary artery disease: FRISC II prospective randomized multicenter study. Lancet. 1999;354:708–715
  3. Wallentin L, Lagerqvist B, Husted S, et al. Outcome at 1 year after an invasive compared with a non-invasive strategy in unstable coronary artery disease: the FRISC II invasive randomized trial. Lancet. 2000;356:9–16
  4. Cannon CP, Weintraub WS, Demopoulos LA, et al. Comparison of early invasive and conservative strategies in patients with unstable coronary syndromes treated with the glycoprotein IIb/IIIa inhibitor tirofiban. N. Engl. J. Med. 2001;344:1879–1887
  5. Fox KA, Poole-Wilson PA, Henderson RA, et al. Interventional versus conservative treatment for patients with unstable angina or non–ST-segment elevation myocardial infarction: the British Heart Foundation RITA-3 randomised trial. Lancet. 2002;360:743–751
  6. Boden WE. “Routine invasive” versus “selective invasive” approaches to non–ST-segment elevation acute coronary syndromes management in the post-stent/platelet inhibition era. J. Am. Coll. Cardiol. 2003;41:113S–122S
  7. Boden WE. Interpreting new treatment guidelines for non–ST-segment elevation acute coronary syndromes. Am. J. Cardiol. 2001;88(8A):19K–24K
  8. Al-Mukhaini M, Eisenberg MJ, Horlick E. Functional status and quality of life following non–Q wave myocardial infarction. Can. J. Cardiol. 2002;18:1059–1066
  9. Weintraub WS, Culler SD, Kosinski A, et al. Economics, health-related quality of life, and cost-effectiveness methods for the TACTICS (Treat Angina with Aggrastat [tirofiban] and Determine Cost of Therapy with Invasive or Conservative Strategy)-TIMI 18 trial. Am. J. Cardiol. 1999;83:317–322
  10. Janzon M, Levin L, Swahn E. Invasive treatment in unstable coronary artery disease promotes health-related quality of life: results from the FRISC II trial. Am. Heart J. 2004;148:114–121
  11. Mahoney EM, Jurkovitz C, Spertus J, et al. Changes in Seattle Angina Questionnaire (SAQ) scores following treatment for acute coronary syndromes: a follow-up evaluation from TACTICS-TIMI 18 Trial. Eur. Heart J. 2001;22(Suppl S):718
  12. Hlatky MA, Boineau RE, Higginbotham MB, et al. A brief self-administered questionnaire to determine functional capacity (The Duke Activity Status Index). Am. J. Cardiol. 1989;64:651–654
  13. Spertus JA, Winder JA, Dewhurst TA, et al. Development and evaluation of the Seattle Angina Questionnaire: a new functional status measure for coronary artery disease. J. Am. Coll. Cardiol. 1995;25:333–341
  14. Spertus JA, Winder JA, Dewhurst TA, et al. Monitoring the quality of life in patients with coronary artery disease. Am. J. Cardiol. 1994;74:1240–1244
  15. Ware JE, Sherbourne CD. The MOS 36-Item Short-Form Health Survey (SF-36): I. Conceptual framework and item selection. Med. Care. 1992;30:473–483

 This study was supported by the Quebec Foundation for Health Research, Montreal, Quebec, Canada.

PII: S0002-8703(04)00615-5

doi: 10.1016/j.ahj.2004.08.040

American Heart Journal
Volume 149, Issue 5 , Pages 813-819 , May 2005

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