American Heart Journal
Volume 148, Issue 1, Supplement , Pages S9-S13 , July 2004

Statins as the cornerstone of drug therapy for dyslipidemia: monotherapy and combination therapy options

  • Peter H Jones, MD, FACP

      Affiliations

    • Baylor College of Medicine, Houston, Tex, USA
    • Corresponding Author InformationReprint requests: Peter H. Jones, MD, FACP, Associate Professor, Baylor College of Medicine, 6565 Fannin Street, #A601, Houston, TX 77030, USA.

References 

  1. Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults . Executive summary of the third report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III). JAMA. 2001;285:2486–2497
  2. Third Report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III). Final Report. Bethesda (Md): National Cholesterol Education Program, National Heart, Lung and Blood Institute, National Institutes of Health; September 2002. NIH Publication 02-5215
  3. Ballantyne CM, Houri J, Notarbartolo A, et al.  Effect of ezetimibe coadministered with atorvastatin in 628 patients with primary hypercholesterolemia. A prospective, randomized, double-blind trial. Circulation. 2003;107:2409–2415
  4. Kashyap ML, McGovern ME, Berra K, et al.  Long-term safety and efficacy of a once-daily niacin/lovastatin formulation for patients with dyslipidemia. Am J Cardiol. 2002;89:672–678
  5. Brown BG, Zhao X-Q, Chait A, et al.  Simvastatin and niacin, antioxidant vitamins, or the combination for the prevention of coronary disease. N Engl J Med. 2001;345:1583–1592
  6. Prueksaritanont T, Zhao JJ, Ma B, et al.  Mechanistic studies on metabolic interactions between gemfibrozil and statins. J Pharmacol Exp Ther. 2002;301:1042–1051
  7. Davidson MH. Combination therapy for dyslipidemia (safety and regulatory considerations). Am J Cardiol. 2002;90(Suppl):50–60K
  8. Pasternak RC, Smith SC, Bairey-Merz CN, et al.  ACC/AHA/NHLBI clinical advisory on the use and safety of statins. J Am Coll Cardiol. 2002;40:567–572
  9. Jones P, Kafonek S, Laurora I, et al.  Comparative dose efficacy study of atorvastatin versus simvastatin, pravastatin, lovastatin, and fluvastatin in patients with hypercholesterolemia (the CURVES study). Am J Cardiol. 1998;81:582–587
  10. Andrews TC, Ballantyne CM, Hsia JA, et al.  Achieving and maintaining National Cholesterol Education Program low-density lipoprotein cholesterol goals with five statins. Am J Med. 2001;111:185–191
  11. Schuster H, Barter PJ, Stender S, et al.  Effects of switching statins on achievement of lipid goals (Measuring Effective Reductions in Cholesterol Using Rosuvastatin Therapy (MERCURY I) Study). Am Heart J. 2004;147:705–712
  12. Wood D, De Backer G, Faergeman O, et al.  Prevention of coronary heart disease in clinical practice (recommendations of the Second Joint Task Force of European and other Societies on Coronary Prevention). Atherosclerosis. 1998;140:199–270
  13. Jones PH, Davidson MH, Stein EA, et al.  Comparison of the efficacy and safety of rosuvastatin versus atorvastatin, simvastatin, and pravastatin across doses (STELLAR trial). Am J Cardiol. 2003;92:152–160
  14. McKenney JM, Jones PH, Adamczyk MA, et al.  Comparison of the efficacy of rosuvastatin versus atorvastatin, simvastatin, and pravastatin in achieving lipid goals (results from the STELLAR trial). Curr Med Res Opin. 2003;19:689–698
  15. Nissen SE, Tuzcu EM, Schoenhagen P, et al.  Effect of intensive compared with moderate lipid-lowering therapy on progression of coronary atherosclerosis (a randomized controlled trial. REVERSAL Investigators). JAMA. 2004;291:1071–1080
  16. Cannon CP, Braunwald E, McCabe CH, et al.  Intensive versus moderate lipid lowering with statins after acute coronary syndromes. Pravastatin or Atorvastatin Evaluation and Infection Therapy—Thrombolysis in Myocardial Infarction 22 Investigators. N Engl J Med. 2004;350:1495–1504

PII: S0002-8703(04)00227-3

doi: 10.1016/j.ahj.2004.04.026

American Heart Journal
Volume 148, Issue 1, Supplement , Pages S9-S13 , July 2004

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