American Heart Journal
Volume 146, Issue 5 , Pages 811-818 , November 2003

Association of the PURSUIT risk score with predischarge ejection fraction, angiographic severity of coronary artery disease, and mortality in a nonselected, community-based population with non-ST–elevation acute myocardial infarction

  • Emmanouil S Brilakis, MD

      Affiliations

    • Division of Cardiovascular Diseases and Internal Medicine, Mayo Clinic, Rochester, Minn, USA
    • ,
  • R.Scott Wright, MD

      Affiliations

    • Division of Cardiovascular Diseases and Internal Medicine, Mayo Clinic, Rochester, Minn, USA
    • ,
  • Stephen L Kopecky, MD

      Affiliations

    • Division of Cardiovascular Diseases and Internal Medicine, Mayo Clinic, Rochester, Minn, USA
    • ,
  • Nikolaos C Mavrogiorgos, MD

      Affiliations

    • Division of Cardiovascular Diseases and Internal Medicine, Mayo Clinic, Rochester, Minn, USA
    • ,
  • Guy S Reeder, MD

      Affiliations

    • Division of Cardiovascular Diseases and Internal Medicine, Mayo Clinic, Rochester, Minn, USA
    • ,
  • Charanjit S Rihal, MD

      Affiliations

    • Division of Cardiovascular Diseases and Internal Medicine, Mayo Clinic, Rochester, Minn, USA
    • ,
  • Bernard J Gersh, MB, ChB, DPhil

      Affiliations

    • Division of Cardiovascular Diseases and Internal Medicine, Mayo Clinic, Rochester, Minn, USA
    • ,
  • Brent A Williams, MS

      Affiliations

    • Division of Biostatistics, Mayo Clinic, Rochester, Minn, USA
    • ,
  • Ian P Clements, MD

      Affiliations

    • Division of Cardiovascular Diseases and Internal Medicine, Mayo Clinic, Rochester, Minn, USA
    • Corresponding Author InformationReprint requests: Ian P. Clements, MD, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA.

Received 7 August 2002 ,Accepted 5 February 2003.

References 

  1. The PURSUIT Trial Investigators . Inhibition of platelet glycoprotein IIb/IIIa with eptifibatide in patients with acute coronary syndromes. Platelet Glycoprotein IIb/IIIa in Unstable Angina (Receptor Suppression Using Integrilin Therapy). N Engl J Med. 1998;339:436–443
  2. Boersma E, Pieper KS, Steyerberg EW, et al.  Predictors of outcome in patients with acute coronary syndromes without persistent ST-segment elevation (results from an international trial of 9,461 patients. The PURSUIT Investigators). Circulation. 2000;101:2557–2567
  3. Harrington RA. Design and methodology of the PURSUIT trial (evaluating eptifibatide for acute ischemic coronary syndromes. Platelet Glycoprotein IIb-IIIa in Unstable Angina: Receptor Suppression Using Integrilin Therapy). Am J Cardiol. 1997;80:34–38B
  4. Brilakis ES, Wright RS, Kopecky SL, et al.  Bundle branch block as a predictor of long-term survival after acute myocardial infarction. Am J Cardiol. 2001;88:205–209
  5. Gillum RF, Fortmann SP, Prineas RJ, et al.  International diagnostic criteria for acute myocardial infarction and acute stroke. Am Heart J. 1984;108:150–158
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  7. Vlietstra RE, Kronmal RA, Frye RL, et al.  Factors affecting the extent and severity of coronary artery disease in patients enrolled in the coronary artery surgery study. Arteriosclerosis. 1982;2:208–215
  8. Emond M, Mock MB, Davis KB, et al.  Long-term survival of medically treated patients in the Coronary Artery Surgery Study (CASS) Registry. Circulation. 1994;90:2645–2657
  9. Ohman EM, Granger CB, Harrington RA, et al.  Risk stratification and therapeutic decision making in acute coronary syndromes. JAMA. 2000;284:876–878
  10. Antman EM, Cohen M, Bernink PJ, et al.  The TIMI risk score for unstable angina/non-ST elevation MI (a method for prognostication and therapeutic decision making). JAMA. 2000;284:835–842
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  12. Savonitto S, Ardissino D, Granger CB, et al.  Prognostic value of the admission electrocardiogram in acute coronary syndromes. JAMA. 1999;281:707–713
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  14. Cohen M, Demers C, Gurfinkel EP, et al.  A comparison of low-molecular-weight heparin with unfractionated heparin for unstable coronary artery disease (Efficacy and Safety of Subcutaneous Enoxaparin in Non-Q-Wave Coronary Events Study Group). N Engl J Med. 1997;337:447–452
  15. Gibbons RJ, Chatterjee K, Daley J, et al.  ACC/AHA/ACP-ASIM guidelines for the management of patients with chronic stable angina (a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Committee on Management of Patients With Chronic Stable Angina)). J Am Coll Cardiol. 1999;33:2092–2197
  16. Mathew V, Farkouh M, Grill DE, et al.  Clinical risk stratification correlates with the angiographic extent of coronary artery disease in unstable angina. J Am Coll Cardiol. 2001;37:2053–2058
  17. Braunwald E. Unstable angina: diagnosis and management. Rockville (Md): United States Department of Health and Human Services, Public Health Service Agency for Health Care Policy and Research, National Heart, Lung and Blood Institute;1994
  18. Sabatine MS, Januzzi JL, Snapinn S, et al.  A risk score system for predicting adverse outcomes and magnitude of benefit with glycoprotein IIb/IIIa inhibitor therapy in patients with unstable angina pectoris. Am J Cardiol. 2001;88:488–492
  19. Mathew V, Farkouh ME, Gersh BJ, et al.  Early coronary angiography improves long-term survival in unstable angina. Am Heart J. 2001;142:768–774
  20. Ryan TJ, Antman EM, Brooks NH, et al.  1999 Update (ACC/AHA guidelines for the management of patients with acute myocardial infarction. A report of the American College of Cardiology/American Heart Assocation Task Force on Practice Guidelines (Committee on Management of Acute Myocardial Infarction)). J Am Coll Cardiol. 1999;34:890–911
  21. Jha P, Deboer D, Sykora K, et al.  Characteristics and mortality outcomes of thrombolysis trial participants and nonparticipants (a population-based comparison). J Am Coll Cardiol. 1996;27:1335–1342

PII: S0002-8703(03)00455-1

doi: 10.1016/S0002-8703(03)00455-1

American Heart Journal
Volume 146, Issue 5 , Pages 811-818 , November 2003

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