American Heart Journal
Volume 146, Issue 2 , Pages 203-206 , August 2003

Does race matter in heart failure?

  • Clyde W. Yancy, MD

      Affiliations

    • University of Texas Southwestern Medical Center/St Paul University Hospital, Dallas Tex, USA
    • Corresponding Author InformationReprint requests: C. Yancy, MD, UT Southwestern Medical Center, 5323 Harry Hines Blvd, CS7-102, Dallas TX 75390-9047, USA.

References 

  1. Dunlap SH, Mallemala S, Sueta CA, et al. Survival rates are similar between African American and white patients with heart failure. Am Heart J 2003;146:265–72
  2. Yancy CW. Heart failure in African Americans (a cardiovascular enigma). J Card Fail. 2000;6:183–186
  3. Dries DL, Exner DV, Gersh BJ, et al.  Racial differences in the outcome of left ventricular dysfunction. N Engl J Med. 1999;341:298
  4. Exner DV, Dries DL, Domanski MJ, et al.  Lesser response to angiotensin-converting-enzyme inhibitor therapy in black as compared with white patients with left ventricular dysfunction. N Engl J Med. 2001;344:1351–1357
  5. Dries DL, Strong MH, Cooper RS, et al.  Efficacy of angiotensin-converting enzyme inhibition in reducing progression from asymptomatic left ventricular dysfunction to symptomatic heart failure in black and white patients. J Am Coll Cardiol. 2002;40:311–317
  6. Carson P, Ziesche S, Johnson G, et al.  Racial differences in response to therapy for heart failure (analysis of the vasodilator-heart failure trials. Vasodilator-Heart Failure Trial Study Group). J Card Fail. 1999;5:178–187
  7. The Beta-Blocker Evaluation of Survival Trial Investigators. A trial of the beta-blocker bucindolol in patients with advanced chronic heart failure. N Engl J Med. 2001;344:1659–1667
  8. Yancy CW, Fowler MB, Colucci WS, et al.  Race and the response to adrenergic blockade with carvedilol in patients with heart failure. N Engl J Med. 2001;344:1358–1365
  9. Carson P, Fowler MB, Mohacsi P, et al.  Effect of carvedilol in black patients with severe heart failure (results of the COPERNICUS Study). [abstract] Circulation. 2001;104:II-754
  10. Saunders E. Hypertension in minorities: blacks. Am J Hypertens 1995;8:115–9S
  11. August P. TGF Beta-1 overexpressed in African American hypertensives. Proc Natl Acad Sci U S A. 2000;97:3479–3484
  12. McNamara DM, Dennis M, Hollubkov R, et al.  Genetic risk assessment of cardiac events, GRACE. Circulation. 2001;103:1644
  13. Mason DA, Moore JD, Green SA, et al.  A gain of function polymorphism in a G-protein coupling domain of the human beta-1 adrenergic receptor. J Biol Chem. 1999;274:12670–12674
  14. Small KM, Wagoner LE, Levin AM, et al.  Synergistic polymorphisms of beta 1 and alpha 2C adrenergic receptors and the risk of congestive heart failure. N Engl J Med. 2002;347:1135–1142
  15. Franciosa JA, Taylor AL, Cohn JN, et al.  African American Heart Failure Trial (A-HeFT) (rationale, design, and methodology). J Card Fail. 2002;8:128–135

PII: S0002-8703(03)00241-2

doi: 10.1016/S0002-8703(03)00241-2

American Heart Journal
Volume 146, Issue 2 , Pages 203-206 , August 2003

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