American Heart Journal
Volume 145, Issue 6 , Pages 1006-1012 , June 2003

Prognostic implication of creatine kinase release after elective percutaneous coronary intervention in the pre-IIb/IIIa antagonist era

  • Ziyad Ghazzal, MD

      Affiliations

    • Andreas Gruentzig Cardiovascular Center of Emory University School of Medicine, Division of Cardiology, Atlanta, Ga, USA
    • Corresponding Author InformationReprint requests: Ziyad Ghazzal, MD, Emory University Hospital, Suite F-606, 1364 Clifton Rd NE, Atlanta GA 30322, USA.
    • ,
  • Salman Ashfaq, MD

      Affiliations

    • Andreas Gruentzig Cardiovascular Center of Emory University School of Medicine, Division of Cardiology, Atlanta, Ga, USA
    • ,
  • Douglas C Morris, MD

      Affiliations

    • Andreas Gruentzig Cardiovascular Center of Emory University School of Medicine, Division of Cardiology, Atlanta, Ga, USA
    • ,
  • John S Douglas, MD

      Affiliations

    • Andreas Gruentzig Cardiovascular Center of Emory University School of Medicine, Division of Cardiology, Atlanta, Ga, USA
    • ,
  • John J Marshall, MD

      Affiliations

    • Andreas Gruentzig Cardiovascular Center of Emory University School of Medicine, Division of Cardiology, Atlanta, Ga, USA
    • ,
  • Spencer B King III, MD

      Affiliations

    • Andreas Gruentzig Cardiovascular Center of Emory University School of Medicine, Division of Cardiology, Atlanta, Ga, USA
    • ,
  • William S Weintraub, MD

      Affiliations

    • Andreas Gruentzig Cardiovascular Center of Emory University School of Medicine, Division of Cardiology, Atlanta, Ga, USA

Received 5 September 2001 ,Accepted 19 August 2002.

References 

  1. Ravkilde J, Nissen H, Mickley H, et al.  Cardiac troponin T and CK-MB mass release after visually successful percutaneous transluminal coronary angioplasty in stable angina pectoris. Am Heart J. 1994;127:13–20
  2. Spadaro JJ, Ludbrook PA, Tiefenbrunn AJ. Paucity of subtle myocardial injury after angioplasty delineated with MB CK. Cathet Cardiovasc Diagn. 1986;12:230–234
  3. Pauletto P, Piccolo D, Scannapieco G, et al.  Changes in myoglobin, creatine kinase-MB after percutaneous transluminal coronary angioplasty for stable angina pectoris. Am J Cardiol. 1987;59:999–1000
  4. Kong TQ, Davidson CJ, Meyers SN, et al.  Prognostic implication of creatine kinase elevation following elective coronary artery. JAMA. 1997;277:461–466
  5. Abdelmeguid AE, Topol EJ, Whitlow PL, et al.  Significance of mild transient release of creatine kinase-MB fraction after percutaneous coronary interventions. Circulation. 1996;4:1528–1536
  6. Abdelmeguid AE, Ellis SG, Sapp SK, et al.  Defining the appropriate threshold of creatine kinase elevation after percutaneous coronary interventions. Am Heart J. 1996;131:1097–1105
  7. Hong MK, Mehran R, Dangas G, et al.  Creatine kinase-MB enzyme elevation following successful saphenous vein graft intervention is associated with late mortality. Circulation. 1999;100:2400–2405
  8. Saucedo JF, Mehran R, Dangas G, et al.  Long-term clinical events following creatine kinase-myocardial band isoenzyme elevation after successful coronary stenting. J Am Coll Cardiol. 2000;35:1134–1141
  9. Klein LW, Kramer BL, Howard E, et al.  Incidence and clinical significance of transient creatine kinase elevations and the diagnosis of non-Q wave myocardial infarction associated with coronary angioplasty. J Am Coll Cardiol. 1991;17:621–626
  10. Oh JK, Shub C, Ilstrup DM, et al.  Creatine kinase release after successful percutaneous transluminal coronary angioplasty. Am Heart J. 1985;109:1225–1231
  11. Kugelmass AD, Cohen CJ, Moscucci M, et al.  Elevation of creatine kinase myocardial isoform following otherwise successful directional coronary atherectomy and stenting. Am J Cardiol. 1994;74:748–754
  12. Kini A, Marmur JD, Kini S, et al.  Creatine kinase-MB elevation after coronary intervention correlates with diffuse atherosclerosis, and low-to-medium level elevation has a benign clinical course (implications for early discharge after coronary intervention). J Am Coll Cardiol. 1999;34:663–671
  13. Stone G, Mehran R, Dangas G, et al.  Differential impact on survival of electrocardiographic Q-wave versus enzymatic myocardial infarction after percutaneous intervention. Circulation. 2001;104:642–647
  14. Antman E, Bassand J, Klein W, et al.  Myocardial infarction redefined a consensus document of the Joint European Society of Cardiology/American College of Cardiology committee for the redefinition of myocardial infarction. The Joint European Society of Cardiology/American College of Cardiology Committee. J Am Coll Cardiol. 2000;36:959–969
  15. Smith SC, Dove JT, Jacobs AK, et al.  ACC/AHA guidelines for percutaneous coronary intervention (revision of the 1993 PTCA guidelines). J Am Coll Cardiol. 2001;37:2215–2238
  16. Narins CR, Miller DP, Califf RM, et al.  The relationship between periprocedural myocardial infarction and subsequent target vessel revascularization following percutaneous coronary revascularization (insights from the EPIC trial. Evaluation of IIb/IIIa platelet receptor antagonist 7E3 in Preventing Ischemic Complications). J Am Coll Cardiol. 1999;33:647–653
  17. The EPILOG Investigators . Platelet glycoprotein IIb/IIIa receptor blockade and low-dose heparin during percutaneous coronary revascularization. N Engl J Med. 1997;336:1689–1696
  18. Tardiff BE, Califf RM, Tcheng JE, et al.  Clinical outcomes after detection of elevated cardiac enzymes in patients undergoing percutaneous intervention. IMPACT-II Investigators. Integrilin (eptifibatide) to Minimize Platelet Aggregation and Coronary Thrombosis-II. J Am Coll Cardiol. 1999;33:88–96
  19. Simmons ML, Harrington R, Califf RM. Minimal myocardial damage during coronary intervention is associated with an impaired outcome. Eur Heart J 20:1112–9
  20. Harrell FE. Design: S functions for biostatistical/epidemiological modeling, testing, estimation, validation, graphics, prediction, and typesetting. Programs available at: statlib@lib.stat.cmu.edu
  21. Laskey WK. Beneficial impact of preconditioning during PTCA on creatine kinase release. Circulation. 1999;99:2085–2089
  22. Liu MW, Douglas JD, Lembo NJ, et al.  Angiographic predictors of a rise in serum creatine kinase (distal embolization) after balloon angioplasty of saphenous vein coronary artery bypass grafts. Am J Cardiol. 1993;72:514–517
  23. Kini A, Kini S, Marmur JD, et al.  Incidence and mechanism of creatine kinase-MB elevation after coronary intervention with different devices. Catheter Cardiovasc Interv. 1999;48:123–129
  24. Lansky AJ, Popma JJ, Leon MB, et al.  Frequency and prognostic importance of creatine phophokinase myocardial isoforms after successful balloon and new device coronary angioplasty. J Invasive Cardiol. 1996;8(C Suppl):3C–9C
  25. Califf RM, Abdelmeguid AE, Kuntz RE, et al.  Myonecrosis after revascularization procedures. J Am Coll Cardiol. 1998;31:241–251

PII: S0002-8703(03)00095-4

doi: 10.1016/S0002-8703(03)00095-4

American Heart Journal
Volume 145, Issue 6 , Pages 1006-1012 , June 2003

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