American Heart Journal
Volume 145, Issue 5 , Pages 795-805, May 2003

Automated three-dimensional assessment of coronary artery anatomy with intravascular ultrasound scanning

  • Jon D Klingensmith, PhD

      Affiliations

    • Department of Biomedical Engineering, Lerner Research Institute, The Cleveland Clinic Foundation, Cleveland, Ohio, USA
  • ,
  • Paul Schoenhagen, MD

      Affiliations

    • Department of Cardiovascular Medicine, The Cleveland Clinic Foundation, Cleveland, Ohio, USA
    • Department of Radiology, Cardiovascular Imaging Center, The Cleveland Clinic Foundation, Cleveland, Ohio, USA
  • ,
  • Azita Tajaddini, DEng

      Affiliations

    • Department of Biomedical Engineering, Lerner Research Institute, The Cleveland Clinic Foundation, Cleveland, Ohio, USA
  • ,
  • Sandra S Halliburton, PhD

      Affiliations

    • Department of Radiology, Cardiovascular Imaging Center, The Cleveland Clinic Foundation, Cleveland, Ohio, USA
  • ,
  • E.Murat Tuzcu, MD, FACC

      Affiliations

    • Department of Cardiovascular Medicine, The Cleveland Clinic Foundation, Cleveland, Ohio, USA
  • ,
  • Steven E Nissen, MD, FACC

      Affiliations

    • Department of Cardiovascular Medicine, The Cleveland Clinic Foundation, Cleveland, Ohio, USA
  • ,
  • D.Geoffrey Vince, PhD

      Affiliations

    • Department of Biomedical Engineering, Lerner Research Institute, The Cleveland Clinic Foundation, Cleveland, Ohio, USA
    • Corresponding Author InformationReprint requests: D. Geoffrey Vince, PhD, Department of Biomedical Engineering, ND20, Lerner Research Institute, The Cleveland Clinic Foundation, 9500 Euclid Ave, Cleveland, OH 44195, USA.

Abstract 

Background

Angiography allows the definition of advanced, severe stages of coronary artery disease, but early atherosclerotic lesions, which do not lead to luminal stenosis, are not identified reliably. In contrast, intravascular ultrasound scanning allows the precise characterization and quantification of a wide range of atherosclerotic lesions, independent of the severity of luminal stenosis.

Methods

Three-dimensional (3-D) reconstruction of entire coronary segments is possible with the integration of sequential 2-dimensional tomographic images and allows volumetric analysis of coronary arteries.

Results

Automated systems able to recognize lumen and vessel borders and to display 3-D images are becoming available.

Conclusion

These systems have the potential for on-line 3-D image reconstruction for clinical decision-making and fast routine volumetric analysis in research studies. This review describes 3-D intravascular ultrasound scanning acquisition, analysis, and processing, and the associated technical challenges.

To access this article, please choose from the options below

Login to an existing account or Register a new account.

  • Purchase this article for 31.50 USD (You must login/register to purchase this article)

    Online access for 24 hours. The PDF version can be downloaded as your permanent record.

  • Subscribe to this title

    Get unlimited online access to this article and all other articles in this title 24/7 for one year.

  • Claim access now

    For current subscribers with Society Membership or Account Number.

  • Visit SciVerse ScienceDirect to see if you have access via your institution.
 

PII: S0002-8703(03)00089-9

doi:10.1016/S0002-8703(03)00089-9

American Heart Journal
Volume 145, Issue 5 , Pages 795-805, May 2003