American Heart Journal
Volume 145, Issue 5 , Pages 751-753 , May 2003

Diagnosing and managing acute pulmonary embolism: role of cardiac troponins

  • Victor F. Tapson, MD

      Affiliations

    • Division of Pulmonary and Critical Care Medicine, Duke University Medical Center, Durham, NC, USA
    • Corresponding Author InformationReprint requests: Dr Victor F. Tapson, Duke University Medical Center, Division of Pulmonary and Critical Care Medicine, 353D Bell Bldg, Durham NC 27710, USA.

References 

  1. Dalen JE, Alpert JS. Natural history of pulmonary embolism. Prog Cardiovasc Dis. 1975;17:257–270
  2. Anderson FA, Jr, Wheeler HB, Goldberg RJ. A population-based perspective of the hospital incidence and case-fatality rates of deep vein thrombosis and pulmonary embolism. Arch Intern Med 1991;151:933-8
  3. Antman EM, Tanasijevic MJ, Thompson B, et al.  Cardiac-specific troponin I levels to predict the risk of mortality in patients with acute coronary syndromes. N Engl J Med. 1996;335:1342–1349
  4. Pacouret G, Schellenberg F, Hamel E, et al.  Troponine I dans l’embolie pulmonaire aigue massive (resultants d’une serie prospective). Presse Med. 1998;27:1627
  5. Giannitsis E, Müller-Bardoff M, Kurowski V, et al.  Independent prognostic value of cardiac troponin T in patients with confirmed pulmonary embolism. Circulation. 2000;102:211–217
  6. Mehta NJ, Jani K, Khan IA. Clinical usefulness and prognostic value of elevated cardiac troponin I levels in acute pulmonary embolism. Am Heart J. 2002;145:821–825
  7. Meyer T, Binder L, Hruska N, et al.  Cardiac troponin I elevation in acute pulmonary embolism is associated with right ventricular dysfunction. J Am Coll Cardiol. 2000;36:1632–1636
  8. Douketis JD, Crowther MA, Stanton EB, et al.  Elevated cardiac troponin levels in patients with submassive pulmonary embolism. Arch Intern Med. 2002;162:79–81
  9. Antman EM. Decision making with cardiac troponin tests. N Engl J Med. 2002;346:2079–2082
  10. Goldhaber SZ. Echocardiography in the management of acute pulmonary embolism. Ann Intern Med. 2002;136(Suppl):691–700
  11. Wolfe MW, Lee RT, Feldstein ML, et al.  Prognostic significance of right ventricular hypokinesis and perfusion lung scan defects in pulmonary embolism. Am Heart J. 1994;127:1371–1375
  12. Wells PS, Anderson DR, Rodger M, et al.  Excluding pulmonary embolism at the bedside without diagnostic imaging (management of patients with suspected pulmonary embolism presenting to the emergency department by using a simple clinical model and D-dimer). Ann Intern Med. 2001;135:98–107

PII: S0002-8703(02)94705-8

doi: 10.1016/S0002-8703(02)94705-8

American Heart Journal
Volume 145, Issue 5 , Pages 751-753 , May 2003

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