American Heart Journal
Volume 143, Issue 2 , Pages 229-234, February 2002

Bivalirudin as a replacement for unfractionated heparin in unstable angina/non-ST-elevation myocardial infarction: Observations from the TIMI 8 trial☆☆

  • Elliott M. Antman, MD

      Affiliations

    • TIMI Study Group Boston, Mass
    • Cardiovascular Division, Department of Medicine, Brigham and Women's Hospital, Boston, Mass
  • ,
  • Carolyn H. McCabe, BS

      Affiliations

    • TIMI Study Group Boston, Mass
    • Cardiovascular Division, Department of Medicine, Brigham and Women's Hospital, Boston, Mass
  • ,
  • Eugene Braunwald, MD

      Affiliations

    • TIMI Study Group Boston, Mass
    • Cardiovascular Division, Department of Medicine, Brigham and Women's Hospital, Boston, Mass
  • ,
  • for the TIMI 8 Investigators

Received 21 December 2000; accepted 2 May 2001.

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 Supported by grants from Biogen, Cambridge, Mass, and The Medicines Company, Cambridge, Mass.

☆☆ Reprint requests: Elliott M. Antman, MD, Cardiovascular Division, Brigham and Women's Hospital, 75 Francis St, Boston, MA 02115. E-mail: eantman@rics.bwh.harvard.edu

PII: S0002-8703(02)39926-5

doi:10.1067/mhj.2002.120405

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  • Improved efficacy and less bleeding: Further evidence of a unique uncoupling of benefit and risk with bivalirudin

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American Heart Journal
Volume 143, Issue 2 , Pages 229-234, February 2002