American Heart Journal
Volume 144, Issue 6 , Pages 1003-1011 , December 2002

Elevated serum creatinine is associated with 1-year mortality after acute myocardial infarction

Received 27 April 2001 ,Accepted 4 April 2002.

References 

  1. US Renal Data System. USRDS 1998 Annual Data Report. Bethesda, Md: : National Institutes of Health and National Institute of Diabetes, Digestive, Kidney Disease; 1998;
  2. Herzog CA, Ma JZ, Collins AJ. Long-term survival of renal transplant recipients in the United States after acute myocardial infarction. Am J Kidney Dis. 2000;36:145–152
  3. Herzog CA, MA JZ, Collins AJ. Poor long-term survival after acute myocardial infarction among patients on long-term dialysis. New Engl J Med. 1998;339:799–805
  4. Sadaniantz A, Wu WC. Survival of renal transplant patients after first myocardial infarction: a look to the past and promises for the future. Am J Kidney Dis. 2000;36:211–213
  5. Chertow GM, Normand SL, Silva LR, et al.  Survival after acute myocardial infarction in patients with end-stage renal disease: results from the cooperative cardiovascular project. Am J Kidney Dis. 2000;35:1044–1051
  6. Culleton BF, Larson MG, Wilson PW, et al.  Cardiovascular disease and mortality in a community-based cohort with mild renal insufficiency. Kidney Int. 1999;56:2214–2219
  7. Marso SP, Ellis SG, Gurm HS, et al.  Proteinuria is a key determinant of death in patients with diabetes after isolated coronary artery bypass grafting. Am Heart J. 2000;139:939–944
  8. Marso SP, Ellis SG, Tuzcu M, et al.  The importance of proteinuria as a determinant of mortality following percutaneouscoronary revascularization in diabetics. J Am Coll Cardiol. 1999;33:1269–1277
  9. Becker BN, Himmelfarb J, Henrich WL, et al.  Reassessing the cardiac risk profile in chronic hemodialysis patients: a hypothesis on the role of oxidant stress and other non-traditional cardiac risk factors. J Am Soc Nephrol. 1997;8:475–486
  10. Venkatesan J, Henrich WL. Anemia, hypertension, and myocardial dysfunction in end-stage renal disease. Semin Nephrol. 1997;17:257–269
  11. Bostom AG, Culleton BF. Hyperhomocysteinemia in chronic renal disease. J Am Soc Nephrol. 1999;10:891–900
  12. Jacobs DRJ, Kroenke C, Crow R, et al.  PREDICT: a simple risk score for clinical severity and long-term prognosis after hospitalization for acute myocardial infarction or unstable angina: the Minnesota heart survey. Circulation. 1999;100:599–607
  13. Matts JP, Karnegis JN, Campos CT, et al.  Serum creatinine as an independent predictor of coronary heart disease mortality in normotensive survivors of myocardial infarction. POSCH Group. J Fam Pract. 1993;36:497–503
  14. McCullough PA, Soman SS, Shah SS, et al.  Risks associated with renal dysfunction in patients in the coronary care unit. J Am Coll Cardiol. 2000;36:679–684
  15. Normand ST, Glickman ME, Sharma RG, et al.  Using admission characteristics to predict short-term mortality from myocardial infarction in elderly patients: results from the Cooperative Cardiovascular Project. JAMA. 1996;275:1322–1328
  16. Schlant RC, Forman S, Stamler J, et al.  The natural history of coronary heart disease: prognostic factors after recovery from myocardial infarction in 2789 men: the 5-year findings of the coronary drug project. Circulation. 1982;66:401–414
  17. Van Ruiswyk J, Hartz A, Kuhn E, et al.  A measure of mortality risk for elderly patients with acute myocardial infarction. Med Decis Making. 1993;13:152–160
  18. Lloyd-Jones DM, Camargo CA, Giugliano RP, et al.  Characteristics and prognosis of patients with suspected acute myocardial infarction and elevated MB relative index but normal total creatine kinase. Am J Cardiol. 1999;84:957–962
  19. Bowers LD, Wong ET. Kinetic serum creatinine assays II: a critical evaluation and review. Clin Chem. 1980;26:555–561
  20. Cockcroft DW, Gault MH. Prediction of creatinine clearance from serum creatinine. Nephron. 1976;16:31–41
  21. Hanley JA, McNeil BJ. The meaning and use of the area under a receiver operating characteristic (ROC) curve. Radiology. 1982;143:29–36
  22. Gurwitz JH, Col NF, Avorn J. The exclusion of the elderly and women from clinical trials in acute myocardial infarction. JAMA. 1992;268:1417–1422
  23. Iezzoni LI, Burnside S, Sickles L, et al.  Coding of acute myocardial infarction: clinical and policy implications. Ann Intern Med. 1988;109:745–751
  24. Kennedy GT, Stern MP, Crawford MH. Miscoding of hospital discharges as acute myocardial infarction: implications for surveillance programs aimed at elucidating trends in coronary artery disease. Am J Cardiol. 1984;53:1000–1002
  25. Foley RN, Parfrey PS, Kent GM, et al.  Serial change in echocardiographic parameters and cardiac failure in end-stage renal disease. J Am Soc Nephrol. 2000;11:912–916
  26. Foley RN, Parfrey PS, Kent GM, et al.  Long-term evolution of cardiomyopathy in dialysis patients. Kidney Int. 1998;54:1720–1725
  27. Hammermeister KE, DeRouen TA, Dodge HT. Variables predictive of survival in patients with coronary disease: selection by univariate and multivariate analyses from the clinical, electrocardiographic, exercise, arteriographic, and quantitative angiographic evaluations. Circulation. 1979;59:421–430
  28. Ryan TJ, Antman EM, Brooks NH, et al.  1999 update: ACC/AHA guidelines for the management of patients with acute myocardial infarction: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Committee on Management of Acute Myocardial Infarction). J Am Coll Cardiol. 1999;34:890–911
  29. Baigent C, Collins R, Appleby P, et al.  ISIS-2: 10 year survival among patients with suspected acute myocardial infarction in randomised comparison of intravenous streptokinase, oral aspirin, both, or neither. The ISIS-2 (Second International Study of Infarct Survival) Collaborative Group. BMJ. 1998;316:1337–1343
  30. The Beta-Blocker Pooling Project (BBPP): subgroup findings from randomized trials in post infarction patients. The Beta-Blocker Pooling Project Research Group. Eur Heart J. 1988;9:8–16
  31. Pfeffer MA, Braunwald E, Moye LA, et al.  Effect of captopril on mortality and morbidity in patients with left ventricular dysfunction after myocardial infarction: results of the survival and ventricular enlargement trial. The SAVE Investigators. N Engl J Med. 1992;327:669–677
  32. Mann JF, Gerstein HC, Pogue J, et al.  Renal insufficiency as a predictor of cardiovascular outcomes and the impact of ramipril: the HOPE randomized trial. Ann Intern Med. 2001;134:629–636
  33. Wallentin L, Lagerqvist B, Husted S, et al.  Outcome at 1 year after an invasive compared with a non-invasive strategy in unstable coronary-artery disease: the FRISC II invasive randomised trial. FRISC II Investigators. Fast Revascularisation during Instability in Coronary artery disease. Lancet. 2000;356:9–16
  34. Mangano CM, Diamondstone LS, Ramsay JG, et al.  Renal dysfunction after myocardial revascularization: risk factors, adverse outcomes, and hospital resource utilization. The Multicenter Study of Perioperative Ischemia Research Group. Ann Intern Med. 1998;128:194–203
  35. Phillips DR, Scarborough RM. Clinical pharmacology of eptifibatide. Am J Cardiol. 1997;80:11B–20B
  36. Hirsh J, Warkentin TE, Raschke R, et al.  Heparin and low-molecular-weight heparin: mechanisms of action, pharmacokinetics, dosing considerations, monitoring, efficacy, and safety. Chest. 1998;114:489S–510S
  37. Lefevre G, Duval M, Gauron S, et al.  Effect of renal impairment on the pharmacokinetics and pharmacodynamics of desirudin. Clin Pharmacol Ther. 1997;62:50–59
  38. Perrone RD, Madias NE, Levey AS. Serum creatinine as an index of renal function: new insights into old concepts. Clin Chem. 1992;38:1933–1953

 Supported in part by grants HL-03533 and HL-07575, from the National Institutes of Health, Bethesda, Md.

☆☆ Reprint requests: Christopher J. O'Donnell, MD, MPH, Premium Heart Study, 73 Mount Wayte Ave, Framingham, MA 01702.

 E-mail: chris@fram.nhlbi.nih.gov

PII: S0002-8703(02)00224-7

doi: 10.1067/mhj.2002.125504

American Heart Journal
Volume 144, Issue 6 , Pages 1003-1011 , December 2002