« Previous
Next »
American Heart Journal
Volume 144, Issue 6
, Pages 941-947
, December 2002
The relevance of subgroup-specific treatment effects: The Studies Of Left Ventricular Dysfunction (SOLVD) revisited
References
- . An evidence based approach to individualising treatment. BMJ. 1995;311:1356–1359
- . Large trials with simple protocols: indications and contraindications. Control Clin Trials. 1989;10:151S–160S
- . Can overall results of clinical trials be applied to all patients?. Lancet. 1995;345:1616–1619
- . What do the overall results of clinical trials and meta-analyses tell us about the efficacy of treatments?. J Nephrol. 1997;10:5–6
-
.
Subgroups, treatment effects, and baseline risks: some lessons from major cardiovascular trials.
Am Heart J. 2000;130:952–961
- . Effect of enalapril on survival in patients with reduced left ventricular ejection fractions and congestive heart failure. N Engl J Med. 1991;325:293–302
- . Effect of enalapril on mortality and the development of heart failure in asymptomatic patients with reduced left ventricular ejection fractions. N Engl J Med. 1992;327:685–691
-
.
Statistics in epidemiology: the case-control study.
J Am Stat Assoc. 1996;91:14–28
- . Stratification by multivariate confounder score. Am J Epidemiol. 1976;104:609–620
-
.
Applied logistic regression.
In: New York: : Wiley; 1989;p. 135–175
-
.
Primer of applied regression and analysis of variance.
In: New York: McGraw-Hill;; 1990;p. 531
-
.
Applied logistic regression.
In: New York: : Wiley; 1989;p. 131
- The independent effects of left ventricular ejection fraction on short-term outcomes and resource utilization following hospitalization for heart failure. Clin Cardiol. 1999;22:184–190
- Influence on prognosis and morbidity of left ventricular ejection fraction with and without signs of left ventricular failure after acute myocardial infarction. Am J Cardiol. 1988;61:1165–1171
- Course and prognosis in patients ≥70 years of age with congestive heart failure and normal versus abnormal left ventricular ejection fraction. Am J Cardiol. 1997;79:216–219
- Acute myocardial infarction in diabetes mellitus and significance of congestive heart failure as a prognostic factor. Am J Cardiol. 1988;62:665–669
- Value of radionuclide rest and exercise left ventricular ejection fraction in assessing survival of patients after thrombolytic therapy for acute myocardial infarction: results of Thrombolysis in Myocardial Infarction (TIMI) phase II study. The TIMI Study Group. J Am Coll Cardiol. 1995;26:73–79
- Mild systolic dysfunction in heart failure (left ventricular ejection fraction > 35%): baseline characteristics, prognosis and response to therapy in the Vasodilator in Heart Failure Trials (V-HeFT). J Am Coll Cardiol. 1996;27:642–649
- Prognostic significance of serial changes in left ventricular ejection fraction in patients with congestive heart failure. The V-HeFT VA Cooperative Studies Group. Circulation. 1993;87:VI17–VI23
- Royal College Lecture, 1976: preoperative left ventricular ejection fraction and survival after coronary artery surgery. Can J Surg. 1976;19:487–493
- Clinical characteristics, left and right ventricular ejection fraction, and long-term prognosis in patients with non-insulin-dependent diabetes surviving an acute myocardial infarction. Diabet Med. 1996;13:450–456
- Diabetes mellitus, a predictor of morbidity and mortality in the Studies of Left Ventricular Dysfunction (SOLVD) trials and registry. Am J Cardiol. 1996;77:1017–1020
- Antiplatelet agents and survival: a cohort analysis from the Studies of Left Ventricular Dysfunction (SOLVD) trial. J Am Coll Cardiol. 1998;31:419–425
- . The effect of digoxin on mortality and morbidity in patients with heart failure. N Engl J Med. 1997;336:525–533
- . Within trial variation—a false trail?. J Clin Epidemiol. 1998;51:301–303
- . Subgroup analysis. Lancet. 1988;2:31–34
- . Assessing apparent treatment-covariate interactions in randomized clinical trials. Stat Med. 1985;4:255–263
- . Analysis of clinical trial outcomes: some comments on subgroup analyses. Control Clin Trials. 1989;10:187S–194S
- Avoidance of large biases and large random errors in the assessment of moderate treatment effects: The need for systematic overviews. Stat Med. 1987;6:245–250
- . The problem of cogent subgroups: a clinicostatistical tragedy. J Clin Epidemiol. 1998;51:297–299
- . Testing for qualitative interactions between treatment effects and patient subsets. Biometrics. 1985;41:361–372
- Subgroup analysis of clinical trials. Am J Cardiol. 1991;67:330–332
- Can treatment that is helpful on average be harmful to some patients? a study of the conflicting information needs of clinical inquiry and drug regulation. J Clin Epidemiol. 1996;49:395–400
- On reaching the tunnel at the end of the light. J Clin Epidemiol. 1997;50:753–755
-
Clinical versus statistical considerations in the design and analysis of clinical research.
J Clin Epidemiol. 1998;4:305–307
- . A consumer's guide to subgroup analyses. Ann Intern Med. 1992;116:78–84
-
.
Statistical aspects of cancer trials.
In: London: : Chapman & Hall; 1982;p. 867–871
-
.
Strategies for subgroup analysis in clinical trials: recent results.
Cancer Res. 1988;111:49–54
- . Analysis of clinical trial outcomes: alternative approaches to subgroup analysis. Control Clin Trials. 1989;10:176S–186S
- . On wisdom after the event. J Clin Epidemiol. 1997;50:749–751
- . Patient subsets and variation in therapeutic efficacy. Br J Clin Pharmacol. 1982;14:473–482
- . The use and abuse of subgroup analysis in epidemiological research. Prev Med. 1987;16:183–194
- Analysis and interpretation of treatment effects in subgroups of patients in randomized clinical trials. JAMA. 1991;266:93–98
- Effects of an angiotensin-converting-enzyme inhibitor, ramipril, on cardiovascular events in high-risk patients. N Engl J Med. 2000;342:145–153
- Effect of amlodipine on morbidity and mortality in severe chronic heart failure. N Engl J Med. 1996;335:1107–1114
-
Praise-2. Prospective randomized amlodipine survival evaluation-2. Presented at: Proceedings of the 49th American College of Cardiology Meeting; March 12-15, 2000; Anaheim, Calif.
☆ Reprint requests: Andrea B. Parker, MSc, Cardiac Research Inc, 15 Oakley Pl, Toronto, Ontario, M2P 2G3 Canada.
☆☆ E-mail: abp.care@sympatico.ca
PII: S0002-8703(02)00218-1
doi: 10.1067/mhj.2002.126446
© 2002 Mosby, Inc. All rights reserved.
« Previous
Next »
American Heart Journal
Volume 144, Issue 6
, Pages 941-947
, December 2002
