American Heart Journal
Volume 144, Issue 5 , Pages 750-752 , November 2002

Risk stratification in acute coronary syndromes: The need for continued vigilance in “low-risk” patients

References 

  1. Hutter AM, Amsterdam EA, Jaffe AS. Task Force 2: acute coronary syndromes: section 2B-chest discomfort evaluation in the hospital. J Am Coll Cardiol. 2000;35:853–862
  2. Hamm CW, Ravkilde J, Gerhardt W, et al.  The prognostic value of serum troponin T in unstable angina. N Engl J Med. 1992;327:146–150
  3. Gerhardt W, Katus H, Ravkilde J, et al.  S-Troponin T in suspected ischemic myocardial injury compared with mass and catalytic concentration of S-creatine kinase isoenzyme MB. Clin Chem. 1991;37:1405–1411
  4. Stubbs P, Collinson P, Moseley D, et al.  Prospective study of the role of cardiac troponin-T in patients admitted with unstable angina. BMJ. 1996;313:262–264
  5. Ohman EM, Armstrong PW, Christenson RH, et al.  Cardiac troponin T levels for risk stratification in acute myocardial ischemia. N Engl J Med. 1996;335:1333–1341
  6. Newby LK, Christenson RH, Ohman EM, et al.  Value of serial troponin T measures for early and late risk stratification in patients with acute coronary syndromes. Circulation. 1998;98:1853–1859
  7. Newby LK, Kaplan AL, Granger BB, et al.  Comparison of cardiac troponin T versus creatine kinase-MB for risk stratification in a chest pain evaluation unit. Am J Cardiol. 2000;85:801–805
  8. Newby LK, Storrow AB, Gibler WB, et al.  Bedside multimarker testing for risk stratification in chest pain units. Circulation. 2001;103:1832–1837
  9. Goldman L, Cook EF, Johnson PA, et al.  Prediction of the need for intensive care in patients who come to the emergency departments with acute chest pain. N Engl J Med. 1996;334:1498–1504
  10. Holmvang L, Hasbak P, Clemmensen P, et al.  Very early risk stratification using combined ECG and biochemical assessment in patients with unstable coronary artery disease (A ThRombin Inhibition in Myocardial ischemia [TRIM] substudy). Circulation. 1998;98:2004–2009
  11. Savonitto S, Ardissino D, Granger CB, et al.  Prognostic value of the admission electrocardiogram in acute coronary syndromes. JAMA. 1999;281:707–713
  12. Nyman I, Areskog M, Areskog NH, et al.  Very early risk stratification by electrocardiogram at rest in men with suspected unstable coronary heart disease. J Intern Med. 1993;234:293–301
  13. Jernberg T, Lindahl B. A combination of troponin T and 12-lead electrocardiography: a valuable tool for early prediction of long-term mortality in patients with chest pain without ST-segment elevation. Am Heart J. 2002;144:804–810
  14. Peacock WF IV, Emerman CL, McErlean ES, et al.  Prediction of short and long term outcomes by troponin T levels in low-risk patients evaluated for acute coronary syndromes. Ann Emerg Med. 2000;35:213–220
  15. Jernberg T, Lindahl B, Wallentin L. The combination of a continuous 12-lead ECG and troponin T; a valuable tool for risk stratification during the first 6 hours in patients with chest pain and a non-diagnostic ECG. Eur Heart J. 2000;21:1464–1472
  16. de Lemos JA, Morrow DA, Bentley JH, et al.  The prognostic value of B-type natriuretic peptide in patients with acute coronary syndromes. N Engl J Med. 2001;345:1014–1021
  17. Christenson RH, Duh SH, Sanhai WR, et al.  Characteristics of an albumin cobalt binding test for assessment of acute coronary syndrome patients: a multicenter study. Clin Chem. 2001;47:464–470
  18. Kontos MC, Jesse RL, Anderson FP, et al.  Comparison of myocardial perfusion imaging and cardiac troponin I in patients admitted to the emergency department with chest pain. Circulation. 1999;99:2073–2078

 Reprint requests: E. Magnus Ohman, MD, UNC-Chapel Hill, Division of Cardiology, 338 Burnett-Womack Building, CB# 7075, Chapel Hill, NC 27599-7075.

☆☆ E-mail: mohman@med.unc.edu

PII: S0002-8703(02)00181-3

doi: 10.1067/mhj.2002.126117

American Heart Journal
Volume 144, Issue 5 , Pages 750-752 , November 2002