American Heart Journal
Volume 143, Issue 6 , Pages 950-951 , June 2002

Making positive out of negative trials

Received 1 November 2001 ,Accepted 5 December 2001.

References 

  1. Weiss EJ, Bray PF, Tayback M, et al.  A polymorphism of a platelet glycoprotein receptor as an inherited risk factor for coronary thrombosis. N Engl J Med. 1996;334:1090–1094
  2. Mikkelsson J, Perola M, Laippala P, et al.  Glycoprotein IIIa/PlA polymorphism associates with progression of coronary artery disease and with myocardial infarction in an autopsy series of middle-aged men who died suddenly. Arteroscler Thromb Vasc Biol. 1999;19:2573–2578
  3. Mikkelsson J, Perola M, Laippala P, et al.  Glycoprotein IIIa/PlA polymorphism associates with progression of coronary artery disease and with myocardial infarction in an autopsy series of middle-aged men who died suddenly. Arteroscler Thromb Vasc Biol. 1999;19:2573–2578
  4. Laule M, Cascorbi I, Stangl V, et al.  A1/A2 polymorphism of glycoprotein IIIa and association with excess procedural risk for coronary catheter interventions: a case-controlled study. Lancet. 1999;353:708–712
  5. Moye LA. Random research. Circulation. 2001;103:3150–3153
  6. Winkelmann BR, Hager J, Kraus WE, et al.  Genetics of coronary heart disease: current knowledge and research principles. Am Heart J. 2000;140(Suppl):S11–S26

 Reprint requests: David E. Kandzari, MD, PO Box 31203, Duke University Medical Center, Durham, NC 27710.

☆☆ E-mail: kandz002@onyx.dcri.duke.edu

PII: S0002-8703(02)00006-6

doi: 10.1067/mhj.2002.122513

American Heart Journal
Volume 143, Issue 6 , Pages 950-951 , June 2002