Imaging and Diagnostic TestingReproducibility of exaggerated blood pressure response to exercise in healthy patients☆
Section snippets
Study population
We conducted an observational, retrospective study.
The Israeli Defense Force maintains a periodical examination center for its personnel. Patients undergo medical check-ups at 3-year intervals. Aside from the stress testing, each examination includes a medical interview, physical examination, electrocardiography, and blood sampling for fasting glucose level and lipid profile. Stress test ergometry was performed in all patients >39 years of age and/or having ≥2 risk factors for cardiovascular
Baseline characteristics
When comparing the patients’ data between the groups at the time the first ExBPR occurred, the concordant group showed no characteristic feature (Table I).Parameter Concordant group (n = 18) Discordant group (n = 99) Control group (n = 81) Age (y) 36.5 ± 2.8 36.8 ± 4.2 35 ± 4.1 BMI (kg/m2) 25.5 ± 2.8 24.6 ± 2.9 24.2 ± 2.7 Fasting glucose (mg/dL) 98.4 ± 23.5 88.9 ± 15.7 89.7 ± 16.7 Cholesterol (mg/dL) 209 ± 33.7 208.2 ± 39.4 192.2 ± 43*
Discussion
Our study shows that for most of the patients with ExBPR, the high blood pressure measurements during stress are not reproducible. The change in SBP from rest to exercise also showed little reproducibility in the ExBPR responders. Those with consistent ExBPR are a relatively small number of patients who could not be distinguished by any clinically significant parameter, although SBP at rest and after 3 minutes of recovery was higher in both study groups than in the control group. Our findings,
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Reprint requests: Dr Yehonatan Sharabi, Internal Medicine D, Chaim Sheba Medical Center, Tel-Hashomer, 52621, Israel. E-mail: [email protected]